SAXENDA®

WEIGHT LOSS INJECTIONS

PRESCRIBED TO OVER 1 MILLION PATIENTS 

 
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SAXENDA®

SAXENDA® is an MHRA & FDA approved injectable medication that is used to aid in weight loss, ultimately improving overall health and wellbeing. In clinical trials, it assists with weight loss and other conditions associated with a high BMI, such as pre-diabetes and sleep apnoea.

Proven results as demonstrated in clinical trials

Lose three times more weight using Saxenda® versus placebo

Improve quality of life

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WHO IS IT FOR?

SAXENDA® is a weight loss injection pen that is indicated as an adjunct to a reduced-calorie diet, and increased physical activity for weight management in adult patients with an initial Body Mass Index (BMI) of:

≥30 kg/m² (obese); or

≥27 kg/m² to <30 kg/m² (overweight) in the presence of at least one weight-related comorbidity such as dysglycaemia (pre-diabetes or type 2 diabetes mellitus), hypertension, dyslipidaemia or obstructive sleep apnoea.

You should check your BMI on the NHS website prior to booking an appointment with us for this service. Simply type 'BMI calculator NHS' into your search bar and follow the instructions

Download Patient Leaflet - click the icon

 

HOW DOES IT WORK?

SAXENDA® is a once daily injection glucagon-like peptide-1 (GLP-1) analogue, indicated as an adjunct to a reduced calorie diet and increased physical activity for weight loss / weight management. 

The exact mechanic of action is not entirely understood. GLP-1 is a physiological regulator of appetite and thus food intake; as SAXENDA® is similar to native GLP-1 it works in brain to decrease your appetite, thereby reducing food intake. Since it's inception, SAXENDA® has been prescribed to over 1 million patients.

Watch the video to learn more.

 
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RESULTS

Results are weight loss, and improved health and well-being.

COST

£350 (first month)

£299 (subsequent months)

First month includes full consultation and 12 week weight loss plan. You will be reviewed in clinic after 16 weeks.

SAXENDA® FAQ's

DOWNLOAD THE FULL PATIENT LEAFLET HERE:

 

 

WHAT IS SAXENDA®?

Saxenda® is a weight loss medicine that contains the active substance liraglutide. It is similar to a naturally occurring hormone called glucagon-like peptide-1 (GLP-1), that is released from our intestines after eating a meal. Although the exact mechanism of action is not fully understood, it is believed that Saxenda® works by suppressing certain receptors in the brain that control your appetite. This causes you to feel fuller, and therefore and less hungry. In turn, this may help you eat less, and reduce your body weight.

AM I SUITABLE?

You may be suitable for treatment with Saxenda if:

- You have a BMI of over 27 with an existing co-morbidity, such as pre-diabetes, type 2 diabetes, high blood pressure, dyslipidaemia, or obstructive sleep apnoea

- You have a BMI of over 30 (with or without any additional co-morbidities as mentioned above)

- You are able and willing to commit to a healthier eating and exercise plan

- You are able and willing to take the prescribed medication properly

WHEN CAN I EXPECT TO SEE WEIGHT LOSS RESULTS? IS IT GOOD?

Weight loss normally starts within two weeks of starting Saxenda.

Saxenda / Skinny Jab is licensed for weight loss by both the MHRA and FDA, and clinical trial report clinically significant weight loss.

Nevertheless, the rate at which you will lose weight and how much weight you will lose is dependent on several factors, including your own personal circumstances, compliance with any associated weight loss plan, compliance with the dosing schedule, and how your body responds to the GLP-1 hormone. 

Saxenda is licensed for weight loss in conjunction with a low calorie diet and exercise: taking Saxenda alone, without making any other lifestyle changes, is unlikely to price the results you want. 

You must follow dose escalations carefully.

Note that the majority of patients taking Saxenda will lose a significant amount of weight. However, some patients are unresponsive to Liraglutide (the active GLP-1 substance in Saxenda) and therefore do not lose any weight / as much weight as expected. 

If you have not lost at least 5% of your starting body weight 12 weeks after commencing the 3mg dose daily, Saxenda is not the right choice for you, and you may wish to consider other weight loss strategies. 

WHAT OTHER BENEFITS CAN SAXENDA OFFER ME?

Clinical trials have shown that the use of Saxenda in clinically obese patients not only increased weight loss, but also helped with associated health problems by nature of having lost the weight, and reduce the risk of developing type 2 diabetes. 

IS IT SAFE?

Saxenda is very safe when appropriately prescribed and and is taken correctly.

IS THERE ANYONE NOT SUITABLE FOR SAXENDA?

You are not suitable for Saxenda if:

- You have a BMI of less than 27

- You are under the age of 18

- You are pregnant

- You are breastfeeding

- You have heart failure (class 4)

- You are over the age of 75 years

- You are currently being treated with other medications for weight loss

- You have obesity caused by an endocrinological disorder

- You have obesity secondary to an eating disorder

- You have a personal or family history of Medullary Thyroid

- You have cancer

- You have obesity secondary to treatment with medicinal products that may cause weight gain

- You have severe renal (kidney) impairment

- You have mild, moderate, or severe hepatic (liver) impairment

- You have inflammatory bowel disease

- You have diabetic gastroparesis

- You are taking Warfarin (speak to your GP as more frequent INR testing is recommended)

- You have a hypersensivity to Liraglutide, disodium phosphate dihydrate, propylene glycol, phenol, hydrochloric acid, sodium hydroxide, or water for injections

WHAT IF I MISS A DOSE?

- If it has been more than 12 hours since the last dose was taken, another should be taken as soon as possible

- If less than 12 hours remains until the next dose is due, you should not take another dose and simply wait until your next dose is due

** Extra doses / an increase in dose should NOT take place to account for missed doses. Do not take any more doses or a higher dose than you should.

ARE THERE ANY RISKS OR SIDE-EFFECTS?

As with all medications, there is always associated risks of side effects. Saxenda is very safe, FDA and MHRA licensed, and is generally very well tolerated. Remember that not everybody experiences side effects.

The main risks and potential side effects include:

- Nausea, vomiting, diarrhoea, constipation

- Delayed gastric emptying, which could potentially affect the absorption of orally taken medications. 

-Dizziness. Should this occur, it is mainly experienced during the first 3 months of commencing the treatment. Driving or use of machines should be exercised with caution if dizziness occurs.

-Insomnia - of this occurs, it is mainly experienced in the first 3 months of treatment

A full list of potential risks and side effects can be seen in the downloadable patient leaflet attached to this page.

HOW LONG DO I NEED TO TAKE SAXENDA FOR?

You will typically take Saxenda for as long as needed to reach your weight goal. 

There is no risk in taking Saxenda long term to maintain results, if you are a person who loses weight and then finds it comes back on. We will always advise you as to whether you should reduce or stop the dose you are taking.

ARE THERE ANY INTERACTIONS WITH ANY OTHER MEDICINES I MIGHT BE TAKING?

Warfarin and other coumarin derivatives: no interactions study has been performed, however, a clinically relevant interaction with poor solubility or narrow therapeutic window cannot be excluded. Therefore, inititation of Saxenda in patient's taking these medicines should be directed under their own GP, as more frequent monitoring of your INR is recommended.