MEDICAL HAIR RESTORATION CARDIFF
CLINICALLY PROVEN NON SURGICAL TREATMENTS FOR HAIR LOSS
From PRP and polynucleotides to exosomes and scalp microneedling — we offer the most advanced non-surgical hair restoration treatments available, all delivered by qualified medical professionals at our Cardiff clinic.
PRP HAIR RESTORATION CARDIFF
PRP HAIR RESTORATION - THE GOLD STANDARD IN NON SURGICAL HAIR LOSS TREATMENT
PRP (Platelet Rich Plasma) is the most clinically studied hair restoration treatment in the world. Using your own blood's growth factors — including PDGF, VEGF and IGF-1 — injected directly into the scalp to stimulate dormant follicles, reduce inflammation, strengthen hair shafts and restore natural hair density. Suitable for male and female pattern hair loss, hormonal thinning, stress-related shedding and receding hairlines. Multiple large-scale meta-analyses confirm PRP significantly improves both hair density and thickness. No surgery. No downtime. Genuine biological hair restoration from within.
1 hr
From 299 British pounds
PRP Hair Restoration Cardiff | Sebastian Rose Medical Aesthetics
PRP (Platelet Rich Plasma) is the most extensively studied non-surgical hair restoration treatment in the world — and the gold standard against which all newer hair loss treatments are measured. At Sebastian Rose in Cardiff, it is administered exclusively by qualified medical professionals.
How it works
A small sample of your own blood is taken and spun in a centrifuge to isolate the platelet-rich plasma — a concentration of powerful growth factors including PDGF, VEGF and IGF-1. These are injected directly into the scalp at the sites of thinning or loss. Once delivered, they stimulate blood supply to dormant hair follicles, reduce scalp inflammation, strengthen hair shafts and extend the natural growth (anagen) phase of the hair cycle — triggering genuine biological hair restoration from within.
What does it treat?
- Male pattern baldness (androgenetic alopecia)
- Female pattern hair thinning
- Stress-related and hormonal hair loss
- Diffuse thinning across the scalp
- Receding hairline (early to moderate)
- Post-partum hair loss
- Thinning at the crown or parting
Clinically Proven
Multiple large-scale meta-analyses confirm PRP significantly improves hair density and thickness. A 2025 clinical trial confirmed PRP combined with scalp microneedling increases hair density by approximately 30% after 12 weeks. Results are cumulative — the full course of treatment is essential for best outcome.
Your treatment protocol
3–4 sessions spaced 4 weeks apart
Maintenance:
Every 6 months to sustain and build on results
Duration per session:
30–45 minutes
Downtime
None — return to normal activities same day
Before Your Appointment
Wash your hair the morning of treatment. Avoid blood-thinning medications and alcohol 24 hours prior where possible. Inform us of any medications or medical conditions at consultation.
Aftercare:
Avoid washing hair for 6 hours post-treatment. Avoid intense exercise, saunas and swimming for 24 hours. Mild scalp tenderness or redness is normal and resolves quickly.
All treatments performed by qualified medical practitioners.
We use Cellenis - the highest yield of exceptional quality PRP on the market. Cheap PRP centifuges and machines do not create a high enough yield to give you results. Be careful what you pay for when you see this treatment being offered too 'cheaply'!
Sebastian Rose — trusted medical hair restoration across Cardiff, Swansea, Newport, Monmouthshire & South Wales.
POLYNUCLEOTIDE HAIR RESTORATION CARDIFF
PLNEST HAIR - THE NATURAL ALTERNATIVE TO PRP - CLINICALLY PROVEN COMPARABLE RESULTS
Plinest Hair is a next-generation polynucleotide injectable derived from highly purified Italian trout DNA. In a 2025 head-to-head clinical trial against PRP, Plinest Hair demonstrated comparable efficacy — with all patients showing improvement in hair density and quality maintained at both 3 and 6 months. No blood draw required. No downtime. Just clinically proven scalp regeneration from within — reducing the inflammation that causes follicle miniaturisation and reactivating dormant hair follicles naturally.
1 hr
From 199 British pounds
Plinest Hair is a clinically proven polynucleotide injectable derived from highly purified Italian trout DNA — developed by Mastelli, the same laboratory behind our skin polynucleotide treatments. When injected into the scalp, it works at a cellular level to stimulate fibroblasts, reduce the chronic scalp inflammation that causes follicle miniaturisation, activate hair growth factors and support the biological regeneration of the hair follicle environment.
In a 2025 clinical trial directly comparing Plinest Hair against PRP side-by-side on the same patients, all participants showed improvement in both hair density and quality — with results maintained at both 3 and 6 month follow-ups. Plinest Hair demonstrated comparable efficacy to PRP, making it an outstanding standalone treatment and an exceptional partner to PRP in a combined protocol.
Plinest Hair is particularly effective for:
Inflammation-driven hair thinning
Hormonal and stress-related hair loss
Androgenetic alopecia in men and women
Patients wanting a blood-free alternative to PRP
Enhancing and extending PRP results when combined
Protocol:
Weekly injections for 4 weeks, then fortnightly for 3 months.
Maintenance every 6 months.
No downtime — mild scalp redness may occur for 24–48 hours.
Available at Sebastian Rose, Cardiff — serving patients from Swansea, Newport, Monmouthshire and across South Wales.
PRP VERUS POLYNUCLEOTIDES FOR MEDICAL HAIR RESTORATION
WHICH HAIR TREATMENT IS RIGHT FOR YOU?
PRP
Uses your own blood's growth factors — PDGF, VEGF and IGF-1
Injected directly into the scalp to stimulate dormant follicles
Reduces scalp inflammation and strengthens hair shafts
Extends the natural hair growth (anagen) phase
Most extensively studied hair restoration treatment in the world
Results typically visible from session 2–3
Course of 3–4 monthly sessions recommended
Ideal for: moderate to significant hair loss, anyone wanting the most established evidence base
PLNEST
Derived from highly purified Italian trout DNA — no blood draw required
Repairs the scalp environment at a cellular level
Reduces chronic follicle inflammation that causes miniaturisation
Activates hair growth factors and stimulates fibroblast activity
2025 clinical trial shows comparable efficacy to PRP head-to-head
Results visible from month one onwards
Weekly sessions for 4 weeks then fortnightly for 3 months
Ideal for: inflammation-driven thinning, blood-phobic patients, combining with PRP for maximum results
CAN'T DECIDE? COMBINE BOTH FOR MAXIMUM RESULTS
PRP and Plinest Hair polynucleotides work on complementary biological pathways — making them exceptionally powerful when used together.
PRP delivers concentrated growth factors that directly stimulate the follicle, while Plinest Hair repairs the extracellular matrix and eliminates the scalp inflammation that causes progressive follicle miniaturisation.
Combined protocols are increasingly recommended by clinical experts as the most comprehensive non-surgical approach to hair restoration currently available.
At Sebastian Rose, your practitioner will assess your degree of hair loss, scalp health and individual needs to design the optimal programme for you — whether that is PRP alone, Plinest alone, or a combined protocol.
Book a consultation to find out which approach is right for you.
NOT SURE WHICH TREATMENT IS RIGHT FOR YOU?
NOT SURE WHICH TREATMENT IS RIGHT FOR YOU?
Book a hair restoration consultation with one
of our medical practitioners. We will assess
your scalp, degree of hair loss and individual
needs to design a personalised programme —
whether that is PRP, Plinest Hair, a combined
protocol, or a recommendation that another
treatment is more appropriate for you.
HAIR RESTORATION FAQ'S
Is PRP or polynucleotides better for hair loss?
Both are clinically proven and both produce comparable results according to a 2025 head-to-head clinical trial. PRP uses your own blood's growth factors and has the largest evidence base of any non-surgical hair treatment. Polynucleotides (Plinest Hair) work by repairing the scalp environment at a cellular level and require no blood draw. The best choice depends on your individual degree of hair loss, scalp condition and personal preference — your practitioner will advise at consultation. Many patients achieve the best results combining both treatments.
How many sessions of PRP do I need for hair loss?
The clinically recommended initial course is 3–4 sessions spaced approximately 4 weeks apart. Most patients begin to see improvement from session 2–3, with full results visible 3–6 months after completing the course. Maintenance sessions every 6 months are recommended to sustain and build on results.
How many sessions of Plinest Hair do I need?
The official Mastelli protocol for Plinest Hair is 8 sessions in total — 4 sessions every 7–14 days in the initial phase, followed by 4 further sessions every 21–30 days. Results are typically visible after the initial 4 sessions, with continued improvement throughout the full course. Maintenance every 6 months is recommended.
Does PRP actually work for hair loss?
Yes. PRP is the most extensively studied non-surgical hair restoration treatment in the world. Multiple large-scale meta-analyses confirm it significantly improves hair density and thickness, particularly for androgenetic alopecia in both men and women. Results are cumulative and best achieved with a full course of treatment rather than a single session.
Is hair loss treatment painful?
Both PRP and Plinest Hair involve fine needle injections into the scalp. Most patients describe mild discomfort or a tingling sensation rather than significant pain. Topical anaesthetic is available on request. The procedure typically takes 30–45 minutes and you can return to normal activities immediately afterwards.
How long does it take to see results from PRP hair treatment?
Some patients notice reduced shedding and improved scalp condition within 4–6 weeks of their first session. Visible improvement in hair density and thickness typically becomes apparent 2–3 months after beginning treatment, with full results at 6 months. Results continue to improve throughout the course and beyond.
Can women have PRP or Plinest Hair for hair loss?
Yes — both treatments are suitable for women. Female pattern hair loss, hormonal thinning, post-partum hair loss and stress-related shedding all respond well to PRP and Plinest Hair polynucleotides. A full scalp assessment at consultation will confirm which treatment or combination is most appropriate.
What is the difference between PRP and Plinest Hair polynucleotides?
PRP (Platelet Rich Plasma) is derived from your own blood — a small sample is spun to isolate growth factors which are then injected into the scalp to stimulate dormant follicles. Plinest Hair is a ready-to-use injectable derived from purified Italian trout DNA that works by repairing the scalp's cellular environment, reducing inflammation and reactivating follicle activity. Both work on complementary biological pathways — which is why combining them produces the best results.
Is there any downtime after PRP or Plinest Hair treatment?
No — both treatments are no-downtime procedures. Mild scalp redness, tenderness or small injection marks may be visible for 24–48 hours. We recommend avoiding washing your hair for 6 hours after PRP, and avoiding intense exercise, saunas and swimming for 24 hours. You can return to normal activities the same day.
How much does hair restoration treatment cost in Cardiff?
At Sebastian Rose, PRP Hair Restoration starts from £280 per session. Plinest Hair polynucleotide treatment starts from £199 per session. Course pricing is available for both treatments. We also offer Klarna flexible payment at checkout so you can spread the cost of your hair restoration programme.
Am I suitable for hair restoration treatment?
Most adults experiencing early to moderate hair loss are suitable candidates. Both PRP and Plinest Hair are most effective when hair loss is in its earlier stages — dormant follicles can be reactivated, but follicles that have been inactive for many years are less likely to respond. A full scalp assessment at consultation will determine suitability and the most appropriate treatment programme for you. Patients who are pregnant, breastfeeding or have certain blood disorders may not be suitable — please inform us of all medical conditions at consultation.
Can hair restoration treatments be combined with other treatments?
Yes. Scalp microneedling can be added to PRP sessions to increase effectiveness by up to 30% — it is available as an optional add-on at Sebastian Rose. PRP and Plinest Hair can also be combined in a single treatment programme for maximum results. Your practitioner will design the optimal protocol at consultation.
Do you offer hair restoration consultations in Cardiff?
Yes — all patients at Sebastian Rose receive a full scalp assessment and personalised treatment plan before beginning any hair restoration programme. Consultations are free of charge*. We welcome patients from Cardiff, Swansea, Newport, Monmouthshire, Bridgend and across South Wales.
