RADIESSE IN CARDIFF
FOR DEFINITION, FIRMNESS AND NATURAL COLLAGEN.
Content medically reviewed by our GMC / NMC-registered medical professionals. Last updated September 2026.

RADIESSE - FROM MERZ AESTHETICS - USED WORLDWIDE
Radiesse is a calcium hydroxylapatite collagen stimulator from Merz Aesthetics, used by medical professionals around the world. Unlike hyaluronic acid fillers, it works in two ways: its smooth gel gives immediate structure and lift, while its microspheres encourage your skin to produce new collagen and elastin over the following months. The result is firmer, better-defined contours and improved skin quality that continues to develop after treatment.
45 min
From 299 British pounds
WHAT IS RADIESSE?
FOR INSTANT STRUCTURE & LASTING COLLAGEN
What is Radiesse?
Radiesse is an injectable dermal filler and collagen biostimulator. It is made from tiny microspheres of calcium hydroxylapatite, a mineral naturally found in bone, suspended in a smooth gel.
Most dermal fillers are made from hyaluronic acid and simply add volume where they are placed. Radiesse does two jobs. The gel gives instant support and definition, and as it is gradually absorbed, the microspheres act as a scaffold that stimulates your own fibroblast cells to produce new collagen and elastin. Your skin becomes firmer and better supported from within.
Radiesse is CE-marked for use in the UK and Europe and FDA-approved in the United States, and it has been used by medical professionals worldwide for many years.
Hyperdilute Radiesse
When Radiesse is diluted, it adds very little volume and works mainly as a skin-quality treatment. Spread in a fine layer beneath the skin, hyperdilute Radiesse stimulates collagen to improve firmness, crepiness and laxity on areas such as the neck, décolletage and backs of the hands. Your practitioner will advise whether standard or hyperdilute Radiesse, or a combination, suits your goals.
WHAT DOES RADIESSE TREAT?
FOR DEFINITION, SUPPORT & SKIN QUALITY
Radiesse is particularly effective for:
Jawline Definition
Radiesse adds structure along a softening jawline and supports early jowling, creating a sharper, more defined lower face.
Chin Projection
A small amount of Radiesse can improve chin projection and balance the profile, particularly where the chin is set back.
Cheek Structure
Radiesse restores support to the mid-face, lifting and defining the cheeks as volume is lost with age.
Deep Folds and Lines Nasolabial folds (nose-to-mouth lines) and marionette lines can be softened with Radiesse's combination of immediate support and collagen stimulation.
Neck and Décolletage
Hyperdilute Radiesse improves crepey, lax skin on the neck and chest by stimulating new collagen across the area.
Hand Rejuvenation
As the backs of the hands lose volume, veins and tendons become more visible. Radiesse restores volume and improves skin quality for smoother, younger-looking hands.
Where Radiesse is not used
Radiesse is not used in the lips or under the eyes. These areas need a softer, reversible product, and we will recommend alternatives such as Juvelook, biofiller, hyaluronic acid filler, Sunekos, or polynucleotides where appropriate.
IS RADIESSE A DERMAL FILLER?
YES, BUT IT ALSO STIMULATES COLLAGEN. HERE ARE THE KEY DIFFERENCES FROM HYALURONIC ACID FILLER

RADIESSE
How it works
Immediate structure plus stimulates your own collagen
Results appear
Immediately, then improve over 2–3 months
Longevity
Commonly reported 12–18 months (varies)
Suitable for
Jawline, chin, cheeks, deep folds; diluted for neck, décolletage and hands
Reversible?
No
Approved?
CE-marked (UK/EU) and FDA-approved (US)

HYALURONIC ACID FILLER
How it works
Physically adds volume
Results appear
Immediately
Longevity
6–18 months
Suitable for
Whole face - especially lips, mid-cheek and cheekbones, a targeted volume and definition
Reversible?
Yes (with hyaluronidase)
Approved?
CE-marked (UK/EU) and FDA-approved (US)
Many clients choose Radiesse because they want visible definition straight away and firmer skin that keeps improving over the following months. Because it cannot be dissolved, product choice, placement and technique matter even more, which is why every Radiesse treatment at Sebastian-Rose starts with a full facial assessment. If you are deciding between collagen stimulators, read about Sculptra in Cardiff, which builds collagen gradually over a course without immediate volume.
If you want the collagen stimulation of Radiesse with the immediate softness of a hyaluronic acid filler, read about HArmonyCa, which combines both.
AM I SUITABLE FOR RADIESSE?
Ideal Candidates:
You may be an ideal candidate for Radiesse if:
You have lost definition along your jawline, chin or cheeks
You have deep nasolabial folds or marionette lines
You have crepey or lax skin on your neck, décolletage or hands
You want visible structure straight away, with collagen stimulation that continues afterwards
You are in good general health with realistic expectations
You understand that Radiesse cannot be dissolved and are happy to proceed after discussing this at consultation
WHO SHOULD NOT HAVE RADIESSE?
Radiesse may not be suitable if
You are pregnant or breastfeeding
You have an active skin infection or inflammation in the treatment area
You have a history of severe allergic reactions or anaphylaxis, or an allergy to lidocaine
You have a bleeding disorder or are taking blood thinners (this may increase bruising risk)
You have certain autoimmune conditions — your practitioner will assess this at consultation
You have a history of keloid scarring
You want treatment in the lips or under the eyes
A thorough medical consultation is always carried out before any treatment at Sebastian-Rose. We will always tell you honestly if Radiesse is not right for you.
HOW DOES RADIESSE WORK?
How Does Radiesse Work?
Radiesse contains microspheres of calcium hydroxylapatite suspended in a smooth gel. When injected, the gel provides immediate lift and support. Over the following weeks, the gel is naturally absorbed and the microspheres act as a scaffold, stimulating the surrounding fibroblast cells to produce new collagen and elastin. Over time, the microspheres are gradually broken down by the body, while the collagen they stimulated continues to support the skin.
The process happens in three stages:
Stage 1
Immediate (day 1) The gel gives visible structure and definition as soon as treatment is finished.
Stage 2 Settling (weeks 1–2)
Any swelling, tenderness or bruising settles, and the true result becomes clearer.
Stage 3
Collagen Stimulation (weeks 4–12) The microspheres stimulate new collagen and elastin. Skin feels firmer and better supported, and results continue to develop for several months.
WHAT DOES A RADIESSE TREATMENT INVOLVE AT SEBASTIAN ROSE?
Your Consultation
Every Radiesse journey at Sebastian-Rose begins with a consultation. We assess your facial anatomy and skin, discuss your concerns and goals, and decide together whether Radiesse is the right treatment for you. In-clinic treatment consultations are free, but a £50 deposit is required to book. The full deposit is deducted from any treatment you book as a result. If we decide treatment isn't suitable, a £10 fee applies and the remaining £40 is refunded.
We will never recommend a treatment that isn't genuinely right for your face.
Your Treatment Plan
For facial contouring, many patients need a single treatment, with a review to assess the result. For hyperdilute skin tightening on the neck, décolletage or hands, a course of one to two sessions is common, spaced several weeks apart. The number of syringes you need is decided individually at consultation.
The Treatment
Sessions typically take 30–45 minutes. The area is cleaned and numbing cream can be applied for comfort. Radiesse is injected using a fine needle or cannula, and most Radiesse products contain lidocaine, a local anaesthetic, to reduce discomfort. For hyperdilute treatments, Radiesse is mixed with sterile saline and spread evenly across a wider area.
After Your Treatment
You may notice swelling, tenderness, redness or mild bruising for a few days — this is normal. For the first 24 hours, avoid make-up on the treated area, strenuous exercise, alcohol, saunas and heavy pressure on the skin. For hyperdilute treatments, we may advise gentle massage. You will leave with written aftercare instructions.
Follow-Up
We ask all Radiesse clients to return for a review so we can assess the result and advise whether any further treatment is needed.
RADIESSE RESULTS - WHAT TO EXPECT
Radiesse gives a visible result straight away and continues to improve as collagen builds. Here is a realistic timeline:
Immediately: Visible lift and definition in the treated area.
Week 1–2:
Swelling settles and the result becomes clearer.
Week 4–12:
New collagen begins to form. Skin looks and feels firmer, and hyperdilute treatments start to show improved skin quality.
Month 3–6:
Collagen stimulation continues, supporting firmer, better-defined contours.
Month 12–18:
Results are commonly reported to last around 12 to 18 months, although this varies with age, metabolism, the area treated and lifestyle. Maintenance treatments help sustain your results.
HOW MUCH DOES RADIESSE COST IN CARDIFF?
Radiesse Face (1.5ml): from £450
Radiesse Neck and Décolletage (hyperdilute): from £399
Radiesse Hands (hyperdilute): from £399
Additional 1.5ml syringe at the same appointment: £299
The number of syringes required is assessed at your consultation.
We will never recommend more than is clinically necessary.
Flexible Payment Available
Radiesse treatments can be spread across Klarna's flexible payment plans — making this long-lasting treatment more accessible without compromising on quality. Read more about Klarna here.
RADIESSE FAQs
Radiesse Frequently Asked Questions
Where can I get Radiesse in Cardiff? Sebastian-Rose Medical Aesthetics offers Radiesse at 39 Charles Street, Cardiff city centre, CF10 2GB, for patients across Cardiff and South Wales. All treatments are performed by GMC or NMC-registered medical professionals.
How much does Radiesse cost in Cardiff? Radiesse at Sebastian-Rose starts from £399 for hyperdilute neck, décolletage or hand treatment, and from £450 for facial contouring with a 1.5ml syringe. Additional syringes at the same appointment are £299, and Klarna payment options are available.
How long does Radiesse last?
Results are commonly reported to last around 12 to 18 months, and the collagen it stimulates can continue to support the skin. How long results last varies from person to person.
Does Radiesse hurt?
Most Radiesse products contain a local anaesthetic (lidocaine), and numbing cream can also be applied beforehand. Most patients describe mild pressure or discomfort rather than pain.
Is there downtime after Radiesse?
Most people return to normal activities straight away. Swelling, tenderness and bruising can occur and usually settle within a few days.
Can Radiesse be dissolved?
No. Unlike hyaluronic acid filler, Radiesse cannot be dissolved with hyaluronidase. It is broken down naturally by the body over time, which is one reason it is only recommended for suitable areas and patients.
Can Radiesse be used in the lips or under the eyes?
No. Radiesse is not used in the lips or tear troughs. Softer, reversible products or regenerative treatments such as polynucleotides are used in these areas instead.
Should I choose Radiesse or Sculptra?
Radiesse gives immediate structure plus collagen stimulation, which suits jawline, chin and cheek definition. Sculptra builds collagen gradually over a course of treatments without immediate volume. Some patients benefit from both, and the right choice is decided at consultation.
When will I see results from Radiesse?
You will see a difference in structure and definition immediately. Collagen stimulation then develops over the following two to three months, so skin continues to look firmer after treatment.
Can Radiesse be combined with other treatments?
Yes. Radiesse combines well with anti-wrinkle injections, hyaluronic acid filler in other areas, skin boosters and polynucleotides. Your practitioner will advise which combinations are appropriate and in what order.
Is Radiesse safe?
Radiesse has a long track record of use worldwide and is CE-marked and FDA-approved. As with all injectable treatments, risks exist, including bruising, swelling, lumps or nodules and, rarely, the serious risk of filler entering a blood vessel. These risks are minimised by thorough assessment, correct technique and a detailed knowledge of facial anatomy. At Sebastian-Rose, your safety is always our first priority.
Can Radiesse cause lumps?
Lumps or nodules are an uncommon risk and are reduced by correct product choice, placement and technique. Because Radiesse cannot be dissolved, it is not used in areas where lumps are more likely, such as the lips. If you notice any firm lumps after treatment, contact us.
Can I have Radiesse if I have had filler before?
In most cases, yes. We will assess the location and extent of any existing filler at your consultation and advise whether Radiesse is appropriate, or whether you should wait.
Is Radiesse available on the NHS?
No. Radiesse is a cosmetic treatment and is not available on the NHS. It is available privately at Sebastian-Rose Medical Aesthetics Cardiff.
Do you offer Radiesse for men?
Yes. Radiesse is well suited to men seeking stronger jawline and chin definition with a natural result. We welcome clients of all genders.
References
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de Almeida AT, Figueredo V, da Cunha ALG, et al. Consensus recommendations for the use of hyperdiluted calcium hydroxyapatite (Radiesse) as a face and body biostimulatory agent. Plastic and Reconstructive Surgery Global Open. 2019;7(3):e2160.
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Goldie K, Peeters W, Alghoul M, et al. Global consensus guidelines for the injection of diluted and hyperdiluted calcium hydroxylapatite for skin tightening. Dermatologic Surgery. 2018;44(Suppl 1):S32–S41.
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Kadouch JA. Calcium hydroxylapatite: a review on safety and complications. Journal of Cosmetic Dermatology. 2017;16(2):152–161.
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