BIOSTIMULATORS CARDIFF - LONG-TERM COLLAGEN STIMULATION TREATMENTS

Transform your skin from within with advanced biostimulator treatments in Cardiff and South Wales. Unlike traditional dermal fillers that add temporary volume, biostimulators trigger your body's natural collagen and elastin production to rebuild skin structure, restore lost volume, and deliver results that improve over time and last up to 2 years.

At Sebastian Rose Medical Aesthetics, we offer the most comprehensive range of biostimulator treatments in Wales: Sculptra, Profhilo Structura, Radiesse, Ellansé, Juvelook, Polynucleotides, and Exosomes. Each treatment targets different concerns and works through unique mechanisms to stimulate your body's natural regenerative processes for transformative, natural-looking results.

 

WHAT ARE BIOSTIMULATORS?

Biostimulators are injectable treatments that work at the cellular level to activate your body's natural regenerative processes. Rather than simply filling lines or adding volume with hyaluronic acid (which eventually dissolves), biostimulators stimulate fibroblasts—the cells responsible for producing collagen, elastin, and hyaluronic acid—to rebuild your skin's underlying architecture from within.

The result is gradual, natural-looking improvement that develops over weeks and months as your body creates new tissue. Because you're generating your own collagen rather than relying on synthetic materials that dissolve, results last significantly longer—typically 12-24 months compared to 6-12 months for traditional hyaluronic acid fillers.

Biostimulators represent the evolution of aesthetic medicine: treatments that don't just mask aging but actively reverse it by addressing the root cause—progressive collagen loss that begins in our mid-20s and accelerates with age, sun exposure, and environmental stress.

 

HOW DO BIOSTIMULATORS WORK?

Different biostimulators use different mechanisms to trigger collagen production, but all share the same goal: activating your body's natural healing and regenerative processes to create new tissue.

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 - Mechanical Stimulation: Products like Sculptra, Radiesse, and Ellansé contain tiny microspheres (PLLA, CaHA, or PCL) that create a controlled inflammatory response. Your body recognizes these particles as "foreign" and sends fibroblasts to encapsulate them, producing new collagen in the process. Over time, the particles are gradually absorbed while the newly formed collagen remains.

 

 - Chemical Stimulation: Treatments like Profhilo Structura and Juvelook use high-concentration hyaluronic acid combined with amino acids, glycerol, or other bioactive compounds that chemically signal fibroblasts to increase collagen and elastin production while simultaneously hydrating and remodeling tissue.

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 - Genetic Stimulation: Polynucleotides contain DNA fragments that directly activate fibroblast genes responsible for collagen synthesis, elastin production, and tissue repair. They work at the genetic level to "switch on" your body's regenerative pathways.

 

 - Cellular Communication: Exosomes are nano-sized vesicles containing over 300 growth factors, proteins, and genetic material that act as messengers between cells. They deliver biological "instructions" telling your cells to repair damage, reduce inflammation, produce collagen, and restore youthful cellular function.

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All biostimulators share one critical advantage over traditional fillers: they create your own tissue. This means results look completely natural, improve over time rather than degrading, and integrate seamlessly with your facial anatomy without the risk of migration or unnatural appearance.

OUR BIOSTIMULATOR TREATMENTS

SCULPTRA - The Gold Standard Biostimulator

Sculptra is the most established and clinically proven biostimulator, FDA-approved since 2004 and backed by over 20 years of clinical data. It uses poly-L-lactic acid (PLLA)—the same biocompatible, biodegradable material used in dissolvable sutures—to stimulate deep dermal collagen production and gradually restore facial volume.

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How Sculptra Works: Once injected deep into the dermis, PLLA microspheres create a scaffold that triggers fibroblast activation. Over the following weeks and months, your body produces new collagen around these microspheres, gradually rebuilding the skin's structural foundation. The PLLA particles are eventually metabolized into water and carbon dioxide (the same substances your body produces naturally), leaving behind only your own newly formed collagen.

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What Sculptra Treats: Sunken cheeks and temples, deep nasolabial folds, marionette lines, pre-jowl hollowing, overall facial volume loss, chin and jawline contouring, neck and décolletage rejuvenation, buttock augmentation (Sculptra Aesthetic), hand rejuvenation.

Treatment Protocol: Most patients require 2-3 treatment sessions spaced 4-6 weeks apart. Results develop gradually over 3-6 months as collagen production increases, with full results visible at approximately 4-6 months post-final treatment.

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Results Duration: Up to 2 years or longer. Many patients find that results last even longer because once collagen is produced, it becomes part of your tissue structure. Maintenance treatments are typically needed every 18-24 months.

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Ideal Candidates: Those with moderate to severe volume loss, sunken facial features, deep folds, or anyone seeking natural, gradual improvement without the "overfilled" look. Sculptra is particularly effective for patients who have lost significant volume due to aging, weight loss, or illness.

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PROFHILO STRUCTURA - Advanced Bio-Remodeling for Lifting

Profhilo Structura is the next evolution of the famous Profhilo treatment, specifically formulated for areas requiring more structural support, lifting, and volumizing than standard Profhilo provides. It combines ultra-high concentration hyaluronic acid with amino acids and glycerol to create a powerful bio-remodeling effect that targets deeper tissue laxity.

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How Profhilo Structura Works: The unique formulation spreads beneath the skin via a patented NAHYCO® technology, creating a hydrating and lifting network throughout the tissue. The hyaluronic acid provides immediate structure and hydration, while the amino acids (building blocks of collagen) and glycerol (moisture-binding agent) signal fibroblasts to increase collagen and elastin production. This dual-action delivers both immediate improvement and progressive enhancement.

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What Profhilo Structura Treats: Mid-face laxity and sagging, jowl formation, jawline definition and contouring, deeper nasolabial folds, marionette lines, neck laxity, loss of facial contours, cheek volume restoration.

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Treatment Protocol: Typically 2 treatment sessions spaced 4 weeks apart using the BAP (Bio Aesthetic Points) injection technique—5 precise injection points on each side of the face that allow the product to spread naturally through tissue planes.

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Results Duration: 6-12 months. Many patients undergo maintenance treatments twice yearly to sustain results.

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Ideal Candidates: Those with moderate skin laxity, loss of facial contours, jowling, or mid-face sagging who want improvement without traditional fillers. Structura is more powerful than standard Profhilo and targets structural concerns rather than just skin quality.

 

RADIESSE - Immediate Results with Progressive Improvement

Radiesse offers a unique advantage among biostimulators: immediate structural correction combined with long-term collagen stimulation. It uses calcium hydroxylapatite (CaHA) microspheres suspended in a gel carrier, providing instant scaffolding while triggering progressive collagen production over months.

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How Radiesse Works: The gel carrier provides immediate volume and lift upon injection, delivering instant results. Meanwhile, the CaHA microspheres stimulate fibroblast activity and neocollagenesis (new collagen formation). Over 12-18 months, the gel carrier is absorbed while your body gradually replaces it with your own collagen. The CaHA microspheres are eventually metabolized into calcium and phosphate ions—minerals naturally found in your body.

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What Radiesse Treats: Hand rejuvenation (reducing visible veins, tendons, and crepey skin), jawline contouring and definition, chin augmentation, nasolabial folds and marionette lines, cheek volume restoration, neck bands and laxity, temples and pre-jowl areas.

 

Treatment Protocol: Most patients achieve desired results with 1-2 treatment sessions. Radiesse can be diluted for specific applications (like hand rejuvenation) or used at full concentration for structural support.

 

Results Duration: 12-18 months, with many patients experiencing results lasting even longer due to the collagen stimulation effect.

 

Ideal Candidates: Those seeking both immediate improvement and long-term collagen benefits. Radiesse is particularly exceptional for hand rejuvenation and jawline contouring where both instant structure and progressive improvement are desired.

 

ELLANSÉ - Customizable Duration Biostimulator

Ellansé is unique among biostimulators because it offers four different formulations with varying durations—allowing you to choose how long you want results to last. It uses polycaprolactone (PCL) microspheres suspended in a carboxymethylcellulose (CMC) gel carrier for immediate correction plus long-term collagen stimulation.

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How Ellansé Works: The CMC gel carrier provides instant volume and lift, while the PCL microspheres gradually stimulate collagen production. The gel is absorbed within weeks, but the PCL microspheres continue triggering collagen synthesis for months. Eventually, the PCL is completely metabolized, leaving behind only your newly formed collagen.

Ellansé Formulations:

• Ellansé-S: Results last approximately 1 year

• Ellansé-M: Results last approximately 2 years

• Ellansé-L: Results last approximately 3 years

• Ellansé-E: Results last approximately 4 years

What Ellansé Treats: Mid-face volume restoration, cheek augmentation and lifting, nasolabial folds, marionette lines, chin and jawline contouring, temples and under-eye hollowing, hand rejuvenation.

Treatment Protocol: Most patients achieve desired results with 1-2 sessions. The formulation (S, M, L, or E) is chosen based on treatment goals and desired longevity.

Results Duration: 1-4 years depending on formulation chosen. Ellansé offers the longest-lasting results of any biostimulator.

Ideal Candidates: Those who want predictable, long-lasting results without repeated treatments. The ability to choose duration makes Ellansé ideal for patients who want to "test" results with Ellansé-S before committing to longer-lasting formulations.

 

JUVELOOK - Korean Glass Skin Biostimulator

Juvelook represents the perfect fusion of Korean aesthetic philosophy and advanced biostimulation science. This innovative treatment combines hyaluronic acid with PDLLA (Poly-D,L-Lactic Acid) collagen-stimulating microspheres to deliver both immediate hydration and glass-skin glow plus long-term collagen production for lasting improvement.

How Juvelook Works: The hyaluronic acid component provides instant hydration, plumping, and luminosity—creating that coveted Korean "glass skin" effect from day one. Meanwhile, the PDLLA microspheres work beneath the surface over the following weeks and months to stimulate fibroblast activity and trigger natural collagen synthesis, improving skin texture, reducing fine lines, and enhancing overall firmness.

What Juvelook Treats: Under-eye rejuvenation (dark circles, hollowing, fine lines), cheek volumization and lifting, overall skin quality and texture improvement, fine lines and superficial wrinkles, Korean glass skin aesthetic, facial contouring with natural volume.

Treatment Protocol: 2-3 treatment sessions spaced 2-4 weeks apart for optimal results.

Results Duration: 12-18 months—significantly longer than pure hyaluronic acid skin boosters due to the PDLLA collagen-stimulating component.

Ideal Candidates: Those seeking the Korean glass skin aesthetic with long-lasting results, patients wanting both immediate glow and progressive improvement, anyone looking for under-eye rejuvenation with minimal downtime.

 

POLYNUCLEOTIDES - DNA-Based Biostimulators

Polynucleotides are revolutionary DNA-based biostimulators derived from highly purified salmon or trout DNA. These treatments work at the genetic level to activate fibroblast genes responsible for collagen synthesis, elastin production, and tissue repair—essentially "switching on" your body's natural regenerative pathways.

How Polynucleotides Work: DNA fragments (polynucleotides) are injected into the skin where they directly interact with fibroblast cells. These DNA molecules activate specific genes that control collagen production, elastin synthesis, and hyaluronic acid generation. Polynucleotides also possess potent anti-inflammatory and antioxidant properties, protecting skin from free radical damage while promoting cellular repair and regeneration.

What Polynucleotides Treat: Under-eye rejuvenation (dark circles, hollowing, fine lines, crepey skin), neck and décolletage laxity and texture, facial skin quality and radiance, acne scarring and post-inflammatory marks, stretch marks, overall tissue repair and anti-aging.

Available Formulations: Plinest (Italian), Plenhyage (Italian), Newest (French), Rejuran (Korean), Vitaran (Korean), Nucleofill (Italian). Each brand has different molecular weights and concentrations optimized for specific treatment areas.

Treatment Protocol: Typically 2-3 sessions spaced 2-4 weeks apart.

Results Duration: 6-12 months with maintenance treatments recommended.

Ideal Candidates: Those with delicate, thin skin (especially under-eyes), crepey texture, inflammation-related concerns, or anyone seeking improvement in overall skin quality rather than volume. Polynucleotides are exceptionally gentle and safe for sensitive areas.

 

EXOSOMES - Next-Generation Cellular Biostimulation

Exosomes represent the absolute cutting edge of regenerative aesthetic medicine. These nano-sized vesicles (1/1000th the size of a cell) are naturally produced by stem cells and contain over 300 growth factors, proteins, lipids, and genetic material that act as powerful messengers in cellular communication and regeneration.

How Exosomes Work: Unlike other biostimulators that work mechanically or chemically, exosomes function through direct cellular communication. They deliver biological "instructions" and growth factors directly to your skin cells, telling them to repair damaged tissue, reduce inflammation, produce new collagen and elastin, improve cellular metabolism, and restore youthful cellular function. This represents a fundamentally different—and potentially more powerful—approach to skin rejuvenation.

What Exosomes Treat: Overall skin quality and radiance, fine lines and wrinkles, skin laxity and texture concerns, inflammation and redness, scarring and tissue damage, hair loss and scalp rejuvenation, post-procedure healing and recovery.

Treatment Protocol: Typically applied topically post-microneedling or injected directly into tissue. Course of 2-3 treatments spaced 4-6 weeks apart.

Results Duration: 6-12 months, with progressive improvement as cellular regeneration continues.

Ideal Candidates: Those seeking the most advanced regenerative treatment available, patients wanting to address skin aging at the cellular level, anyone looking to enhance results from other treatments (exosomes work synergistically with PRP, polynucleotides, and other biostimulators).

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BIOSTIMULATORS VS DERMAL FILLERS - WHAT'S THE DIFFERENCE?

Dermal Fillers (Hyaluronic Acid): Add volume immediately by filling space with gel, results visible instantly, typically last 6-12 months, work by physically displacing tissue, can migrate or create unnatural appearance if overfilled, provide temporary correction, require ongoing treatments to maintain results, do not improve skin quality.

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Biostimulators: Stimulate your body to create its own collagen and tissue, results develop gradually over weeks/months, typically last 12-24+ months, work by triggering natural biological processes, integrate naturally with your own tissue, provide progressive improvement that continues after treatment, improve overall skin quality not just volume, address root cause of aging (collagen loss).

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Key Difference: Fillers are a temporary solution that adds synthetic material. Biostimulators are a regenerative solution that rebuilds your own tissue. Think of fillers as "painting over" aging while biostimulators "repair the foundation."

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BIOSTIMULATORS VS SKIN BOOSTERS - WHAT'S THE DIFFERENCE?

Skin Boosters (Profhilo, Seventy Hyal, Skinvive, etc.): Focus primarily on hydration and skin quality, contain hyaluronic acid that attracts and holds moisture, provide immediate radiance and glow, improve texture and elasticity through hydration, typically last 6-9 months, best for maintaining already-good skin or addressing dehydration.

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Biostimulators: Focus on collagen production and structural improvement, trigger fibroblast activity to create new tissue, provide progressive improvement over months, address volume loss and deeper structural concerns, typically last 12-24+ months, best for reversing moderate to significant aging or volume loss.

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When to Choose What:

• Skin Boosters: Younger patients (20s-30s) focused on prevention and maintenance, mild dehydration or texture concerns, desire for immediate glow

• Biostimulators: Patients 35+ with visible volume loss, moderate to significant aging signs, deeper structural concerns, desire for long-lasting transformation

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Can They Be Combined? Absolutely! Many patients benefit from using skin boosters for ongoing hydration and radiance maintenance while using biostimulators to address structural volume loss and collagen depletion. This comprehensive approach delivers both immediate glow and long-term regeneration.

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TREATMENT AREAS - WHAT CAN BIOSTIMULATORS TREAT?

Face: Temples (hollowing and volume loss), cheeks (mid-face volume restoration and lifting), nasolabial folds (smile lines), marionette lines (lines from mouth to chin), pre-jowl area (early jowling), jawline (definition and contouring), chin (projection and shape), under-eyes (hollowing, dark circles - polynucleotides only), overall facial volume loss and sagging.

Neck and Décolletage: Neck bands and laxity, crepey skin texture, horizontal neck lines, décolletage wrinkles and sun damage, overall skin quality improvement.

Hands: Volume loss revealing veins and tendons, crepey skin texture, age spots and sun damage, overall hand rejuvenation.

Body: Knee laxity and crepey skin, inner arm laxity, abdomen skin quality (post-weight loss), buttock augmentation (Sculptra), stretch marks, scarring.

Hair and Scalp: Hair loss and thinning (polynucleotides and exosomes), scalp rejuvenation, follicle stimulation.

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RESULTS TIMELINE - WHEN WILL I SEE RESULTS?

Immediate (Day 1): Radiesse, Ellansé, Juvelook, Profhilo Structura provide some immediate correction due to gel carriers. Swelling may also create temporary fullness.

2-4 Weeks: Initial collagen stimulation begins. Profhilo Structura and Juvelook show visible improvement in hydration and radiance. Swelling resolves revealing true baseline.

6-8 Weeks: Progressive collagen production becomes visible. Polynucleotides show improvement in skin quality and texture. Sculptra begins subtle volumization.

3 Months: Significant improvement visible with most biostimulators. Sculptra shows moderate volume restoration. Radiesse and Ellansé show full effect. Juvelook displays both hydration and collagen benefits.

4-6 Months: Peak results for Sculptra and most collagen-stimulating treatments. Maximum volume restoration and skin quality improvement achieved. This is when "before and after" photos show the most dramatic difference.

12-24 Months: Results maintained with gradual, natural aging. Maintenance treatments recommended to sustain benefits. Some patients find results last even longer than clinical studies suggest.

Important Note: Biostimulators require patience. Results are not instant like fillers. However, this gradual improvement is actually an advantage—it looks completely natural, and friends and family will notice you look "refreshed" or "well-rested" rather than "done."

 

HOW LONG DO BIOSTIMULATOR RESULTS LAST?

Polynucleotides: 6-12 months Profhilo Structura: 6-12 months Juvelook: 12-18 monthsRadiesse: 12-18 months Sculptra: 18-24+ months Ellansé-S: Approximately 12 monthsEllansé-M: Approximately 24 months Ellansé-L: Approximately 36 months Ellansé-E:Approximately 48 months Exosomes: 6-12 months (but can enhance other treatments)

Duration varies based on individual metabolism, lifestyle factors (sun exposure, smoking, stress), treatment area (high-movement areas like mouth may metabolize faster), number of sessions (multiple treatments create cumulative collagen), and maintenance schedule.

 

WHO IS A GOOD CANDIDATE FOR BIOSTIMULATORS?

Ideal Candidates: Age 35+ with visible volume loss or collagen depletion, moderate to significant facial aging, sunken temples, cheeks, or under-eyes, deep nasolabial folds or marionette lines, loss of jawline definition or early jowling, crepey skin on face, neck, décolletage, or hands, realistic expectations for gradual improvement, commitment to full treatment course (multiple sessions).

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Excellent Candidates: Those seeking natural-looking results without the "overfilled" appearance, patients who want long-lasting results (12-24+ months), anyone addressing root cause of aging (collagen loss) not just symptoms, those who prefer progressive improvement over instant change, patients wanting to avoid repeated filler appointments.

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Not Ideal Candidates: Those seeking instant, dramatic results (fillers may be better), patients unwilling to commit to multiple sessions, anyone with unrealistic expectations for immediate transformation, those with active skin infections or inflammation, pregnant or breastfeeding women, people with autoimmune conditions (case-by-case basis).

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CAN BIOSTIMULATORS BE COMBINED WITH OTHER TREATMENTS?

Yes! Biostimulators work exceptionally well in combination with other aesthetic treatments:

Biostimulators + Dermal Fillers: Use fillers for precise contouring and immediate correction in specific areas (lips, tear troughs, nose) while using biostimulators to rebuild overall facial volume and structure. This "foundation + finishing" approach delivers both instant results and long-term improvement.

Biostimulators + Skin Boosters: Combine collagen-stimulating treatments with hydrating skin boosters for comprehensive rejuvenation. Biostimulators rebuild structure while skin boosters maintain hydration, radiance, and texture. This is one of the most popular combination protocols.

Biostimulators + PRP/Exosomes: Layer regenerative treatments for enhanced collagen stimulation. For example, Sculptra can be combined with PRP or exosomes in the same session to amplify regenerative signals and accelerate results.

Biostimulators + Polynucleotides: Use volumizing biostimulators (Sculptra, Radiesse, Ellansé) for structural restoration while using polynucleotides to improve delicate areas like under-eyes where volumizing products may be too heavy.

Biostimulators + Energy Devices: Combine with radiofrequency, ultrasound, or laser treatments for comprehensive facial rejuvenation. Energy devices tighten skin while biostimulators restore volume—addressing both laxity and deflation.

Biostimulators + Botox: Address both dynamic wrinkles (muscle movement) and static volume loss. Botox relaxes muscles while biostimulators rebuild underlying structure for complete facial rejuvenation.

 

FREQUENTLY ASKED QUESTIONS

Are biostimulators painful? Discomfort is minimal. We apply topical numbing cream before treatment, and most biostimulators can be mixed with lidocaine (local anesthetic) for additional comfort. Patients typically describe a slight pressure or pinching sensation during injection. Pain levels are comparable to or less than traditional filler treatments.

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What is the downtime after biostimulator treatments? Minimal. Most patients experience mild swelling, redness, and possible bruising at injection sites for 24-72 hours. Makeup can usually be applied the next day. We recommend avoiding strenuous exercise, alcohol, and excessive sun exposure for 24-48 hours post-treatment. You can typically return to work and normal activities immediately, though some patients prefer scheduling treatments before a weekend to allow any swelling to subside.

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How many sessions will I need? This depends on the specific biostimulator and your treatment goals. Sculptra typically requires 2-3 sessions spaced 4-6 weeks apart. Profhilo Structura requires 2 sessions 4 weeks apart. Radiesse and Ellansé often achieve desired results in 1-2 sessions. Polynucleotides and Juvelook typically require 2-3 sessions spaced 2-4 weeks apart. Exosomes are usually 2-3 sessions 4-6 weeks apart. Your practitioner will create a personalized treatment plan during consultation.

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Can I have biostimulators if I have filler already? Yes, in most cases. Biostimulators can be safely layered with existing hyaluronic acid fillers. However, timing and technique matter. During your consultation, inform your practitioner about any previous filler treatments (what product, how much, when, where) so they can create an appropriate treatment plan. In some cases, it may be recommended to dissolve old filler before beginning biostimulator treatments.

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Will biostimulators make me look unnatural or overdone? No! This is actually one of the key advantages of biostimulators. Because they work gradually by stimulating your own collagen production rather than adding large volumes of gel, results look completely natural. Improvement develops slowly over weeks and months, so there's no sudden dramatic change. Friends and family will notice you look refreshed, healthy, and well-rested rather than "done." The gradual nature also allows for treatment adjustment if needed.

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What happens when biostimulator results wear off? Unlike fillers which can sometimes deflate suddenly, biostimulator results fade very gradually. Your newly formed collagen will slowly break down through natural aging processes, but at a much slower rate than the original product. Many patients find results last longer than clinical studies suggest. When you're ready for maintenance, you'll typically need fewer sessions than your initial treatment course because you're building on existing collagen rather than starting from scratch.

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Are there any side effects or risks? Biostimulators have excellent safety profiles when administered by qualified medical professionals. Common temporary side effects include swelling, redness, bruising, tenderness at injection sites, small bumps or nodules under the skin (usually resolve within weeks). Rare complications include infection (minimized with sterile technique), granulomas or persistent nodules (more common with Sculptra if technique is suboptimal), vascular complications (extremely rare, minimized with proper injection technique), allergic reactions (very rare). We conduct thorough medical history review and consultation to identify any contraindications before treatment.

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How do I choose which biostimulator is right for me? This depends on your specific concerns, goals, anatomy, and budget. During your consultation, we'll assess your facial structure, discuss your aesthetic goals, review your medical history, explain which biostimulators are best suited for your concerns, create a personalized treatment plan, and discuss expected results and timelines. Some patients benefit from combining multiple biostimulators—for example, using Sculptra for cheeks and temples while using polynucleotides for under-eyes.

 

Can men have biostimulator treatments? Absolutely! Biostimulators are exceptionally popular with male patients because results are subtle, natural, and masculinity-preserving. Men often experience significant volume loss in temples, cheeks, and jawline as they age, and biostimulators effectively address these concerns without feminizing facial features. Many male patients appreciate the long-lasting results that minimize the need for frequent clinic visits.

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Will I need maintenance treatments? Yes, eventually. While biostimulators last significantly longer than hyaluronic acid fillers (12-24+ months vs 6-12 months), they are not permanent. Your body continues aging, and the newly formed collagen will gradually break down over time. Maintenance treatments are typically needed every 12-24 months depending on the specific product used. The good news: maintenance treatments often require fewer sessions and less product than initial treatment because you're building on existing collagen.

 

Can biostimulators treat under-eye hollowing and dark circles? Some can, some cannot. Polynucleotides are excellent for under-eyes because they're specifically designed for delicate, thin skin. They improve skin quality, reduce dark circles, and gently stimulate collagen without creating lumps or visible product. Juvelook can also be used carefully in the under-eye area. However, volumizing biostimulators like Sculptra, Radiesse, and Ellansé are generally not recommended for under-eyes because the skin is too thin and these products can create visible nodules or irregularities. Traditional hyaluronic acid filler or polynucleotides are better choices for this delicate area.

 

Are biostimulators suitable for all skin types and tones? Yes! Unlike some laser or energy-based treatments that can cause pigmentation issues in darker skin tones, biostimulators work safely and effectively across all skin types and Fitzpatrick phototypes. There is no risk of hyperpigmentation or hypopigmentation with injectable biostimulators.

 

Can I exercise after biostimulator treatments? We recommend avoiding strenuous exercise for 24-48 hours post-treatment to minimize swelling and bruising. Light walking is fine, but avoid high-intensity workouts, hot yoga, heavy lifting, or activities that significantly elevate heart rate and blood pressure. After 48 hours, you can resume normal exercise routines.

 

What should I avoid before biostimulator treatments? To minimize bruising risk, avoid blood-thinning substances for 7-10 days before treatment if medically safe to do so. This includes aspirin, ibuprofen, naproxen (unless prescribed by doctor), fish oil and omega-3 supplements, vitamin E supplements, ginkgo biloba, ginseng, garlic supplements, and excessive alcohol consumption. Do not discontinue any prescription medications without consulting your doctor. Inform your practitioner about all medications and supplements during consultation.

 

Can I combine different biostimulators in one treatment? Yes, this is actually quite common! Many patients benefit from strategic combination of different biostimulators targeting different areas and concerns. For example: Sculptra for deep cheek and temple volume, polynucleotides for under-eyes and skin quality, Radiesse for hand rejuvenation. Your practitioner will create a comprehensive treatment plan that may involve multiple products used strategically across different facial zones.

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How much do biostimulator treatments cost? Costs vary depending on the specific product, treatment area, and amount needed. Package pricing and payment plans are available. Consultation is required for personalised quote based on your specific needs.

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WHY CHOOSE SEBASTIAN ROSE FOR BIOSTIMULATOR TREATMENTS IN CARDIFF?

Medical Expertise: All treatments performed by GMC/NMC-registered medical professionals with advanced training in biostimulator injection techniques and facial anatomy.

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Comprehensive Range: We offer the most complete selection of biostimulators in Wales—Sculptra, Profhilo Structura, Radiesse, Ellansé, Juvelook, Polynucleotides, and Exosomes—allowing us to create truly customized treatment plans.

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Premium Products Only: We use only genuine, FDA/MHRA-approved products from authorized UK distributors. No unlicensed imports or counterfeit materials.

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Natural Results Philosophy: We believe in subtle, natural enhancement that makes you look like the best version of yourself—never overdone or unnatural.

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Personalised Treatment Plans: No cookie-cutter approaches. Every patient receives a customized plan based on their unique facial anatomy, aesthetic goals, and budget.

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Transparent Pricing: Clear, upfront pricing with no hidden fees. Package deals and 0% finance available.

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Central Cardiff Location: Convenient location in Cardiff city centre serving South Wales, Swansea, Newport, and the Vale of Glamorgan.

 

Complementary Consultations: Thorough, no-pressure consultations to discuss your concerns, answer questions, and create a treatment plan.

Aftercare Support: Ongoing support and follow-up to ensure optimal results and patient satisfaction.

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BOOK YOUR BIOSTIMULATOR CONSULTATION IN CARDIFF

Ready to discover how biostimulators can restore your facial volume, stimulate collagen production, and deliver long-lasting, natural-looking results? Book your consultation with Cardiff's biostimulator experts.

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During your consultation, we'll assess your facial structure and aging concerns, discuss your aesthetic goals and expectations, explain which biostimulators are best suited for you, create a personalized treatment plan, answer all your questions, provide transparent pricing, and show you before-and-after results from previous patients.

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Contact Sebastian Rose Medical Aesthetics today to begin your regenerative transformation with Cardiff's most comprehensive biostimulator treatments.

Call 0800 772 0137 or book online