NCTF CARDIFF
UNIQUE INJECTABLE WITH OVER 60 INGREDIENTS FOR OPTIMAL CELL ENVIRONMENT
NCTF 135 - ACTIVATE YOUR SKIN
NCTF 135® HA by FILLMED is the world's most clinically studied mesotherapy treatment — a revolutionary bio-revitalising injectable that delivers 60 active ingredients directly into the skin in a single formula. Unlike standard skin boosters that offer temporary surface hydration, NCTF 135® HA works at a cellular level to genuinely regenerate, repair and rebuild the skin from within. The result? Skin that doesn't just look better — it becomes biologically healthier, more radiant and more youthful over time.
30 min
From 199 British pounds
WHAT IS NCT135® HA??
THE SCIENCE OF CELLULAR SKIN REGENERATION
NCTF stands for New Cellular Treatment Factor — a name that describes exactly what this treatment does.
Developed by FILLMED Laboratories (formerly Filorga) in France, NCTF 135® HA is the only mesotherapy product in the world to combine free non-cross-linked hyaluronic acid with a patented cocktail of 60 active ingredients in a single, highly effective formula.
This is not a filler. This is not a standard skin booster. NCTF 135® HA is a poly-revitalising solution that works biologically and globally on the root causes of skin ageing — not just the surface symptoms.
What's inside each vial:
- 12 vitamins including A, B1, B2, B5, B6, B8, B9, B12, C and E — to stimulate vital cell functions
- 24 amino acids — the building blocks of collagen and elastin
- 6 coenzymes — to catalyse biochemical skin reactions
- 5 nucleic acids — to support DNA repair and cell regeneration
- 6 minerals including Magnesium, Sodium, Potassium and Calcium — to correct deficiencies and restore skin balance
- 2 antioxidants — to neutralise free radicals and protect against environmental damage
- Free non-cross-linked hyaluronic acid (5mg/ml) — for deep hydration without adding volume
60 ingredients. One formula. Unmatched cellular regeneration.
It earned its reputation as the gold standard in mesotherapy across Europe and beyond — and it is exclusively available at Sebastian Rose, administered by qualified medical professionals serving Cardiff, Swansea, Newport, Monmouthshire and South Wales.
HOW DOES NCT135 HA WORK?
CELLULAR REPAIR ON TWO LEVELS - SIMULTANEOUSLY
NCTF 135® HA works on two simultaneous levels to deliver results no single-ingredient skin booster can match:
Level 1 — Immediate Hydration & Radiance (Day 1):
The free non-cross-linked hyaluronic acid provides instant deep hydration, plumping the skin from within and restoring luminosity immediately. Patients often describe a visible glow and improved skin texture from their very first session.
Level 2 — Cellular Regeneration (Weeks 1–12):
The 60 active ingredients — vitamins, amino acids, coenzymes, nucleic acids and minerals — penetrate the epidermis and superficial dermis, nourishing skin cells, stimulating fibroblast activity and triggering the production of new collagen and elastin. Over the following weeks, the skin continues to improve as the cellular repair process builds momentum.
The Science:
Micro-injections deliver the solution via micro-papules into the skin using fine 30G or 32G needles, a cannula, or a mesogun device. The formula diffuses through the skin layers, supporting the natural cell cycle. Because results are cumulative and aligned with the skin's own regeneration cycle — which runs on a 21-day cycle — sessions are spaced 3 weeks apart for optimal outcome.
The Result:
Skin that is genuinely regenerated at a cellular level — not temporarily masked. Hydration, firmness, radiance and elasticity that continue to improve session after session and are maintained with a twice-yearly protocol.
BENEFITS OF NCTF135 HA CARDIFF
WHY IT IS THE WORLD'S MOST PRESCRIBED MESOTHERAPY TREATMENT
Deep Cellular Hydration — Restores moisture at the dermis level, not just the surface
Instant Radiance Boost — Visible glow from session one
Collagen & Elastin Stimulation — Rebuilds the skin's structural proteins naturally
Fine Line Reduction — Smooths and softens superficial wrinkles progressively
Improved Skin Firmness & Tone — Restores density and elasticity to lax skin
Enlarged Pore Reduction — Refines skin texture and minimises pore appearance
Under-Eye Rejuvenation — One of the only treatments suitable for the delicate periorbital zone
Dark Circle Improvement — Improves microcirculation and skin quality around the eyes
Even Skin Tone — Corrects dullness, blemishes and uneven complexion
Free Radical Protection — 2 antioxidants protect against environmental skin damage
Mineral Correction — Replaces Magnesium, Sodium, Potassium and Calcium lost through ageing
Suitable for All Skin Types — Safe across all Fitzpatrick skin types
No Downtime — Return to normal activities the same day
Clinically Proven — Backed by multiple randomised controlled trials including HEBE2 (2019)
Preventive AND Corrective — Treats existing damage while protecting against future ageing
Combines with Other Treatments — Enhances results from Profhilo, microneedling, Juvelook, PRP and more
No Risk of Volume or Distortion — Non-cross-linked HA adds hydration, not volume
WHO IS NCTF135 HA FOR?
IDEAL CANDIDATES FOR BIO-REVITALISING MESOTHERAPY
NCTF 135® HA is suitable for adults of all ages seeking genuine skin improvement. It is both preventive and corrective — equally effective for someone in their late 20s wanting to protect their skin, and someone in their 50s or 60s looking to restore what time has taken.
NCTF 135® HA is ideal for:
- Dehydrated, dry or dull skin lacking radiance
- Tired or stressed skin that looks fatigued
- Fine lines and early superficial wrinkles
- Loss of skin firmness, density and elasticity
- Uneven skin tone, blemishes or pigmentation
- Enlarged pores and rough skin texture
- Under-eye concerns — dark circles, hollowing, crepiness
- Sun-damaged or post-summer skin
- Anyone wanting a natural, no-downtime skin rejuvenation
- Those wanting to enhance or maintain results from other treatments
- Patients who have tried standard skin boosters and want something more powerful
Treatment areas include:
Face — Neck — Décolletage — Back of Hands — Under-Eye (Periorbital) — Inner Arms — Abdomen
Not suitable for:
Pregnant or breastfeeding women. Those with known allergies to hyaluronic acid or any formula components. Active skin infection or inflammation in the treatment area. Please inform us of all medications and medical conditions at consultation.
NCTF 135 HA TIMELINE & TREATMENT PROTOCOL
CLINICALLY RECOMMENDED PROGRAMME
Number of Sessions:
The clinically recommended protocol — validated in the HEBE2 multicentre trial across 147 subjects — is 3 sessions spaced 3 weeks apart, aligned with the skin's natural 21-day cell regeneration cycle.
Treatment Process:
1. Skin consultation and assessment
2. Cleansing and topical anaesthetic application if required (15 minutes)
3. Micro-injection technique using fine needle or mesogun device (15–30 minutes)
4. Post-treatment soothing and aftercare instructions
Results Timeline:
Immediately: Improved radiance and hydration visible from day one
Week 3: Skin texture visibly smoother; second session administered
Week 6: Continued improvement in firmness, tone and luminosity; third session administered
Week 12 (Day 75): Peak cumulative results — significant reduction in fine lines and wrinkles, improved radiance scores clinically demonstrated as superior to anti-ageing skincare alone
Months 6–12: Maintained results with ongoing collagen stimulation
Maintenance:
A minimum of 2 full treatment protocols per year is recommended to sustain and build on results. Many patients choose quarterly single top-up sessions between full courses. Results are cumulative — the skin continues to improve with each protocol.
Single session or full course options are available at checkout.
NCTF 135 HA VERSUS OTHER TREATMENTS
WHY CHOOSE THE WOWRLD'S GOLD STANDARD?
NCTF 135® HA vs Standard Skin Boosters
Standard boosters: Single-ingredient HA for surface hydration
NCTF 135® HA: 60 active ingredients including HA — addresses hydration AND cellular regeneration simultaneously
Verdict: NCTF 135® HA delivers deeper, more comprehensive and longer-lasting results
NCTF 135® HA vs Profhilo:
Profhilo: High-concentration pure HA for tissue remodelling and hydration
NCTF 135® HA: HA plus vitamins, amino acids, minerals, coenzymes — repairs at a nutritional and cellular level
Verdict: Different mechanisms — both excellent. NCTF 135® HA is superior for skin quality, texture and radiance. They combine very well together.
NCTF 135® HA vs Juvelook:
Juvelook: HA + PDLLA for immediate hydration and long-term collagen stimulation via bio-remodelling
NCTF 135® HA: HA + 59 nutritive ingredients for cellular repair and regeneration
Verdict: Complementary treatments. Juvelook for structural collagen building; NCTF 135® HA for cellular nutrition and radiance. Combined protocols are exceptionally powerful.
NCTF 135® HA vs Microneedling:
Microneedling: Creates micro-channels to stimulate collagen via controlled injury
NCTF 135® HA: Delivers active ingredients directly into the dermis via micro-injection
Verdict: NCTF 135® HA can be used alongside or instead of microneedling. Combined protocols amplify results significantly.
NCTF 135® HA vs Anti-Ageing Skincare:
In the HEBE2 randomised controlled trial (2019), 3 sessions of NCTF 135® HA produced results significantly superior to twice-daily anti-ageing moisturiser alone — at day 75 and day 120.
Verdict: No topical product can replicate injectables delivered directly to the dermis.
NCTF 135 HA FREQUENTLY ASKED QUESTIONS
EVERYTHING YOU NEED TO KNOW
Is NCTF 135® HA painful?
Discomfort is minimal. The needles used are extremely fine (30G or 32G) and the microdroplet injection technique means the sensation is brief. We also offer specialist 'Nanosoft' needles, which means you barely feel anything at all! Topical anaesthetic is available on request. Most patients describe a mild stinging sensation that resolves immediately.
How long does the treatment take?
Each session takes approximately 30 minutes. Allow 45 minutes for your first appointment, which includes a full skin consultation and assessment.
Is there any downtime?
No. NCTF 135® HA is a no-downtime treatment. Mild redness, small papules or slight swelling may appear immediately after and typically resolves within a few hours to 48 hours. You can return to normal activities the same day. Avoid makeup, sun exposure, intense exercise and touching the treated area for 24 hours.
When will I see results?
Many patients notice an improvement in radiance and hydration from the very first session. Results are cumulative — the most significant improvements are seen after completing the full 3-session protocol, with continued improvement for weeks afterwards.
How long do results last?
Results from a full 3-session protocol are typically maintained for 4–6 months. With the recommended twice-yearly maintenance programme, results build progressively over time as cumulative collagen stimulation continues.
How many sessions do I need?
The clinically recommended protocol is 3 sessions spaced 3 weeks apart. Single sessions and full courses are available at checkout. For long-term results, a minimum of 2 full protocols per year is recommended.
Can NCTF 135® HA be combined with other treatments?
Yes — and it works exceptionally well in combination. NCTF 135® HA pairs powerfully with Sunekos, Profhilo, Juvelook, microneedling, PRP, anti-wrinkle injections and many other treatments we do, such as Sculptra and dermal filler. Your practitioner will advise on the optimal combination protocol at consultation.
Is NCTF 135® HA safe?
Yes. NCTF 135® HA has been extensively studied in multiple randomised controlled clinical trials and has an excellent safety profile. It is CE marked and used by medical professionals across Europe. As with all injectable treatments, it must be administered by a qualified medical practitioner.
Who performs the treatment at Sebastian Rose?
All NCTF 135® HA treatments at Sebastian Rose are performed exclusively by qualified medical professionals. Your safety and results are our highest priority.
Can I have NCTF 135® HA if I have had fillers?
In most cases, yes. Please disclose all previous treatments at consultation so your practitioner can advise appropriately.
