MESOTHERAPY, CHEMICAL PEELS & SKIN BOOSTERS
A wide range of skin boosters, from Juvelook to Skinvive, Rejuran to Teosyal; chemical peels from BioRePeel to Jessners to Obagi - all designed to rejuvenate, refresh, and maintain the health of your skin. Offering premium French, Swiss, Italian, and Korean formulations and more.
Chemical Peels.
BioRePeel CL3 · Obagi Blue Peel Radiance · Jessner's Peel · Medical-grade skin resurfacing for acne, pigmentation, anti-ageing and texture. No-downtime options available. All skin types.
1 hr
From 99 British pounds
45 min
From 99 British pounds
30 min
From 80 British pounds
Exosomes: Next-Generation Regenerative Therapy
Exosomes are powerful nano-messengers containing 300+ growth factors that communicate directly with your skin cells to accelerate repair, stimulate collagen, and enhance regeneration at the cellular level. This cutting-edge therapy improves skin quality, reduces inflammation, and supports long-term rejuvenation for transformative, science-backed results.
30 min
From 299 British pounds
EXOSOMES — THE FUTURE OF SKIN REGENERATION
Exosomes are not a skincare trend. They are one of the most significant advances in regenerative medicine of the last decade — and their application in aesthetics is only beginning to be understood.
Derived from stem cells, exosomes are nano-sized extracellular vesicles that act as biological messengers between cells. They carry over 300 growth factors, proteins, lipids and genetic information directly into your skin cells — instructing them to repair, regenerate and behave as younger, healthier cells do.
Unlike topical skincare, which cannot penetrate below the epidermis, exosomes work at a cellular level — triggering genuine biological change rather than surface-level improvement.
At Sebastian Rose we use Purasomes — delivering 20 billion exosomes per treatment. The results are not cosmetic in the traditional sense. Patients experience measurable improvement in skin quality, texture, tone, hydration and elasticity — with progressive improvement continuing for weeks after treatment as the cellular repair process unfolds.
Exosomes are particularly powerful when used alongside microneedling, where the micro-channels created allow direct delivery of exosomes into the dermis — dramatically enhancing uptake and results compared to either treatment alone. They are also highly effective for hair restoration and scalp health.
Who is it for?
Anyone experiencing accelerated skin ageing, chronic skin dullness, post-inflammatory changes, acne scarring, sun damage, or anyone who simply wants the most advanced skin regeneration treatment currently available. Exosomes work on all skin types and tones with no downtime.
This is not a maintenance facial.
This is biological skin repair.
HYDROMAX
Vivacy Hydromax (Stylage Hydromax): Deep Hydration Skin Booster
Hydromax is a premium hyaluronic acid skin booster enhanced with sorbitol for intense, long-lasting hydration. Injected into the skin's deeper layers, it plumps, smooths fine lines, and restores radiance from within. This gentle yet effective treatment improves skin quality, texture, and luminosity for naturally refreshed, hydrated skin.
15 min
From 249 British pounds
VIVACY HYDROMAX — DEEP SKIN HYDRATION & BIOREVITALISATION CARDIFF
Not all skin boosters are equal.
Vivacy Hydromax — part of the Stylage range from Laboratoires Vivacy, one of France's most respected aesthetic medicine manufacturers — stands apart from standard hyaluronic acid skin boosters through a formulation that addresses not just hydration, but the biological environment in which hydration is maintained.
Hydromax combines non-crosslinked hyaluronic acid with mannitol — a powerful antioxidant. This combination is clinically significant. When any injectable product is administered, the needle creates a micro-inflammatory response that generates free radicals — and free radicals actively accelerate the degradation of injected hyaluronic acid. Mannitol acts as a direct scavenger of these hydroxyl radicals, neutralising them at the point of injection and protecting the hyaluronic acid from premature breakdown. The result is a skin booster that hydrates more deeply, lasts longer, and triggers less post-treatment swelling than standard hyaluronic acid alone.
The clinical data behind Hydromax is impressive.
Vivacy's own Skin3 Complex — the mechanism underpinning the product — demonstrates a 188% increase in epidermal stem cell proliferation, a 53% increase in Collagen XVII production, a 238% increase in ceramides, and a 301% increase in Aquaporin 3, the protein responsible for water transport through the skin. In a patient satisfaction survey of 30 treated patients, 96% reported a substantial improvement in skin quality following treatment. In practice, what patients notice is this: skin that looks genuinely hydrated rather than plumped, a visible improvement in texture and luminosity, reduced fine lines, improved elasticity, and a refreshed quality to the skin that builds progressively across a course of treatment.
Treatment areas include the face, neck, décolletage and hands.
A course of two to three sessions spaced three to four weeks apart is recommended, with maintenance every six months. Results are visible from the first session and continue to develop over two to four weeks.
Hydromax is not a filler. It does not add volume or alter structure. It restores the skin's hydration, resilience and biological function from within — and for patients whose primary concern is skin quality rather than volume loss, it is one of the most effective injectable treatments available.
Juvelook: Korean Bio-Remodeling Skin Booster
Juvelook is a revolutionary Korean skin booster combining hyaluronic acid with PDLLA (poly-D, L-lactic acid) collagen stimulators. This dual-action treatment delivers immediate hydration while triggering long-term collagen production for improved skin texture, reduced fine lines, and enhanced radiance. Particularly effective for under-eye rejuvenation, Juvelook remodels skin from within for natural, lasting results.
30 min
From 250 British pounds
JUVELOOK — HYBRID BIOSTIMULATOR CARDIFF | PDLLA + HYALURONIC ACID
Juvelook is not a skin booster in the traditional sense. It is a hybrid biostimulator — and that distinction matters enormously when it comes to what it can actually achieve for your skin.
Most injectable skin treatments work in one of two ways: they either hydrate the skin using hyaluronic acid, or they stimulate collagen production using a biostimulatory ingredient. Juvelook does both simultaneously, in a single formulation. Originating from South Korea, it combines 42.5mg of PDLLA (Poly-D,L-Lactic Acid) — a biodegradable collagen-stimulating polymer — with non-crosslinked hyaluronic acid in one patented formula. The result is a treatment that delivers immediate visible improvement while triggering a sustained biological regeneration process that continues for months after the last session.
Here is how it works in practice.
The hyaluronic acid component acts immediately — binding water within the dermis, restoring hydration, plumping the skin and producing the dewy, refreshed quality that patients notice within days of treatment. As the hyaluronic acid gradually metabolises over the following weeks, the PDLLA microparticles take over — activating fibroblast cells, the skin's collagen-producing factories, to generate new Type I and Type III collagen and elastin fibres in the deeper layers of the dermis. This collagen production continues to build progressively for up to six months after treatment, meaning results do not peak immediately — they improve over time.
What patients experience across a course of Juvelook treatment is a genuine transformation in skin quality. Pores refine. Acne scarring softens. Fine lines reduce. Skin texture becomes smoother and more consistent. Elasticity improves. The skin develops a structural resilience that surface-level hydration treatments cannot provide. Results from a full course of three sessions typically last six to twelve months, with some patients experiencing improvement well beyond that as the newly formed collagen continues to provide structural support.
Juvelook is particularly well suited to patients with acne scarring, enlarged pores, skin laxity, fine lines, or those who have noticed a general decline in skin quality and want a treatment that addresses the underlying cause — collagen loss — rather than simply masking the symptoms. It is safe for all skin types, can be used on the face, under-eye area, neck and décolletage, and has an excellent safety profile with minimal downtime.
A course of two to three sessions spaced four weeks apart is recommended, followed by maintenance every nine to twelve months.
Medical Microneedling: Collagen Induction Therapy
Medical-grade microneedling uses fine needles to create controlled micro-injuries in the skin, triggering your body's natural healing response to stimulate collagen and elastin production. This advanced treatment improves skin texture, reduces acne scars, minimizes pores, diminishes fine lines, and enhances overall skin quality. Can be combined with PRP, skin boosters, or exosomes for amplified regenerative results.
30 min
From 140 British pounds
MEDICAL MICRONEEDLING CARDIFF — COLLAGEN INDUCTION THERAPY
Microneedling is one of the most clinically proven skin treatments available — and one of the most misunderstood. Not all microneedling is the same. The depth of needle penetration, the sterility of the environment, the qualification of the practitioner, and the actives applied during treatment determine whether you get genuine dermal remodelling or a superficial result that fades within weeks.
At Sebastian Rose, microneedling is a medical procedure. We use clinical-grade devices capable of reaching depths of up to 2mm into the dermis — where collagen and elastin are actually produced. This is the level at which real collagen induction therapy occurs. Beauty salon microneedling is legally restricted to superficial depths only. At-home derma rollers go shallower still, carry infection risk, and cannot replicate the precision of a calibrated medical device.
What sets our microneedling apart further is what we combine it with. Microneedling creates thousands of micro-channels in the skin — and we use those channels to drive powerful actives directly into the dermis at concentrations that topical application could never achieve. Depending on your skin and your goals, we can infuse exosomes, PRP, polynucleotides, Sunekos or bespoke treatment serums — each chosen for what your skin specifically needs.
Medical microneedling at Sebastian Rose treats acne scarring, fine lines, skin laxity, hyperpigmentation, uneven texture, sun damage, stretch marks and general skin quality. It is effective on all skin types and tones, with minimal downtime — typically 24 to 48 hours of mild redness only.
Results are visible after a single session. Optimal results build across a course of three to six treatments. This is one of the highest-value treatments we offer — and one of the most versatile.
Korean Microtox: Glass Skin Botox Treatment
Microtox uses superficial botulinum toxin injections to refine pores, control oil production, and create the coveted Korean "glass skin" effect. Unlike traditional botox that targets muscles, Microtox treats the skin itself for an airbrushed, luminous, poreless complexion without affecting facial expression. Ideal for oily skin and achieving flawless K-beauty perfection.
1 hr
250 British pounds
MICROTOX — KOREAN GLASS SKIN CARDIFF
Microtox is one of the most requested treatments at Sebastian Rose — and one that consistently surprises patients who assumed botulinum toxin was only for wrinkles.
This is not anti-wrinkle treatment. Microtox involves the intradermal injection of highly diluted botulinum toxin across the surface of the skin — not into the underlying muscles. At this superficial depth, it targets the sebaceous glands responsible for excess oil production, the eccrine sweat glands that contribute to shine, and the superficial musculature that creates skin texture irregularities. The result is the Korean glass skin effect that social media has made famous — but delivered clinically, with precision, by medical professionals who understand the anatomy involved.
What patients actually notice in the days following treatment: refined pores, significantly reduced oiliness and shine, an airbrushed smoothness to the skin surface, and a luminosity that no topical product replicates. The skin looks genuinely different — not plumped, not frozen, not altered in structure. Simply better in quality.
Microtox works best on a well-maintained skin foundation. We are consistently honest with patients about this: the results will be limited and shorter-lived if the skin underneath is dehydrated, congested or poorly maintained at home. The patients who get the most from Microtox use a medical-grade cleanser, a retinoid, daily SPF, and have addressed any active skin concerns before booking. If that foundation is not yet in place, we will always recommend building it first — through our medical skincare range, a course of treatments, or both.
Microtox is a complement to good skin health. When the two work together, the results are genuinely exceptional.
Results last three to four months.
A consultation is required before treatment to confirm suitability.
NCTF 135® HA by FILLMED — the original French skin booster known globally as the Chanel Injection.
A scientifically advanced cocktail of 59 active ingredients including hyaluronic acid, 12 vitamins, 24 amino acids, 6 minerals, 6 coenzymes and 5 nucleic acids, delivered directly into the dermis to stimulate fibroblast activity, boost collagen production and restore radiant, healthy skin from within.
30 min
From 199 British pounds
NCTF 135® HA — FILLMED | THE ORIGINAL SKIN BOOSTER CARDIFF
Before skin boosters were a trend, there was NCTF 135 HA.
Created in 1978 by Dr Michel Tordjman — a French aesthetic doctor and cellular biologist — NCTF 135 HA was the original injectable skin nutrition treatment. Developed not as a cosmetic product but as a clinical solution to cellular skin ageing, it remains nearly five decades later one of the most comprehensively formulated, clinically evidenced and widely trusted skin booster treatments in the world. FILLMED, its manufacturer, obtained MDR certification in February 2025 — the most rigorous medical device regulation in Europe — further reinforcing its exceptional safety and scientific credibility.
NCTF stands for New Cellular Treatment Factor. The name captures exactly what it does. Rather than delivering a single active ingredient, NCTF 135 HA provides the skin with a complete cellular environment — a precisely balanced cocktail of 59 active ingredients that are naturally present in healthy, youthful skin and progressively depleted through ageing, UV exposure and environmental damage.
The formula contains hyaluronic acid at high molecular weight for deep dermal hydration, 12 vitamins including Vitamins A, B-complex, C and E for cellular repair, antioxidant protection and collagen synthesis, 24 amino acids — the most comprehensive amino acid complex of any skin booster — providing all the raw materials fibroblasts require to produce new collagen and elastin, 6 minerals including calcium and zinc to support biochemical skin function, 6 coenzymes to enhance fibroblast metabolic activity, 5 nucleic acids as building blocks for new skin cell formation, and glutathione as a master antioxidant to neutralise free radicals and protect against premature skin ageing.
This is not a hydration treatment with some added vitamins. It is a complete nutritional protocol for the dermis — delivering everything skin cells need to function optimally, repair damage and regenerate — in a single injectable solution.
The clinical evidence is substantial. A randomised, prospective, controlled, multicentre study published in the Journal of Dermatologic
Treatment demonstrated that NCTF 135 HA significantly reduced superficial wrinkles across the face, neck and décolletage at day 75 and day 120 compared to control — results that were statistically significant and clinically meaningful. The treatment stimulates fibroblast activity by up to 135% — hence the name. Patient satisfaction across clinical trials consistently exceeds 95%.
In Asia, NCTF 135 HA is known as the Chanel Injection — a nickname earned through its reputation for producing a distinctive luminosity and skin quality improvement that patients describe as their skin looking its absolute best. It is the treatment Korean aesthetics practitioners reach for when the goal is not correction, but perfection of skin quality.
At Sebastian Rose it is delivered via the Nanosoft micro-needling technique or classic injection, depending on treatment area and patient preference. It is suitable for the face including under-eye area, neck, décolletage, hands and inner arms.
A course of three sessions spaced two to three weeks apart is standard, with maintenance every three to five months for optimal cumulative results. Results are immediate and progressive — the glow is visible the same day. The improvement in skin quality builds over weeks.
This is the treatment that started everything.
Polynucleotides: DNA-Based Skin Regeneration
Polynucleotides are cutting-edge DNA-based biostimulators that trigger cellular regeneration, repair damaged tissue, and stimulate collagen production at the deepest level. We offer premium Italian, French, and Korean formulations including Plinest, Plenhyage, Newest, Rejuran, and Vitaran—each containing purified DNA fragments that activate fibroblasts, boost hydration, improve elasticity, and restore youthful skin naturally. Particularly effective for under-eye rejuvenation, acne scarring, pigmentation, and overall skin quality enhancement.
15 min
From 199 British pounds
POLYNUCLEOTIDES — PDRN SKIN REGENERATION CARDIFF
Polynucleotides — also known as PDRN (polydeoxyribonucleotides) — represent one of the most significant shifts in regenerative aesthetics of the last decade. Originally approved in Italy in 1994 for wound healing and tissue repair, their application in aesthetic medicine has grown rapidly as the clinical evidence base has expanded. This is not a trend. It is a treatment with genuine, peer-reviewed science behind it, published across multiple medical journals and validated in randomised controlled trials.
So what are they? Polynucleotides are highly purified DNA fragments — long-chain nucleic acid polymers derived from salmon or trout sperm DNA — that are biocompatible with human tissue. When injected into the skin, they work through two primary mechanisms. First, they activate adenosine A2A receptors, triggering a cascade that stimulates collagen and elastin synthesis, promotes angiogenesis — the formation of new blood vessels that nourish the skin — and modulates inflammation. Second, they enter the salvage pathway of DNA synthesis, providing the raw nucleotide building blocks that cells need to repair and regenerate. The net effect is genuine biological skin repair — not surface-level improvement, but cellular-level regeneration.
Clinically, polynucleotides have been shown to increase skin thickness, improve skin elasticity, reduce wrinkle depth, improve hydration, reduce hyperpigmentation, and support hair follicle health. They have an outstanding safety profile with only minor transient side effects reported across the clinical literature. A 2025 systematic review published in the Journal of Cosmetic Dermatology confirmed polynucleotides as a natural, effective and safe option for skin rejuvenation with multiple benefits and minimal adverse events.
At Sebastian Rose we offer a carefully selected range of premium polynucleotide brands — including Mastelli, Plinest, Newest, Plenhyage, Vitaran and Rejuran — chosen based on clinical performance, purity and the specific needs of each patient. Not all polynucleotide products are equivalent in molecular weight, concentration or formulation. We choose the right product for your skin, your concern and your treatment goals at consultation.
Polynucleotides are particularly effective for skin quality restoration, fine lines, crepey or thin skin, acne scarring, dark circles, under-eye rejuvenation, and hair loss. Results develop progressively over four to eight weeks and last six to twelve months. A course of two to three sessions spaced four weeks apart is typically recommended.
This is regenerative medicine applied to aesthetics. And it works.
REJURAN
Rejuran: Korean Salmon DNA Skin Healer
Rejuran is a revolutionary Korean polynucleotide (PN) and PDRN treatment using purified salmon DNA to repair damaged skin, stimulate collagen production, and restore skin health at the cellular level. This powerful biostimulator triggers natural regeneration, improves elasticity, reduces fine lines, heals acne scars, and enhances overall skin quality. Particularly renowned for under-eye rejuvenation and treating thin, fragile, or damaged skin with long-lasting regenerative results.
30 min
From 199 British pounds
REJURAN — KOREAN SKIN HEALER CARDIFF
Rejuran is the original Korean skin booster — and one of the most trusted polynucleotide treatments in the world. Developed by PharmaResearch in South Korea, it has been used across Asia for over a decade and has built one of the strongest real-world evidence bases of any injectable skin treatment currently available. Its reputation in Korean aesthetic medicine is not marketing. It is the result of thousands of treated patients and consistent, reproducible outcomes.
Rejuran contains high-purity polynucleotides derived from wild salmon DNA — long-chain DNA fragments that are highly biocompatible with human skin. Once injected intradermally, these fragments do not simply hydrate or temporarily plump the skin. They work at a cellular level to activate the skin's own repair and regeneration processes — stimulating fibroblast activity, collagen and elastin synthesis, angiogenesis, and the restoration of a healthy extracellular matrix. The result is skin that is structurally stronger, more resilient, and genuinely healthier — not cosmetically corrected, but biologically improved.
At Sebastian Rose we offer the full Rejuran range, with the specific formulation chosen at consultation based on your skin concerns and goals. Rejuran Healer is the original all-rounder — the go-to formulation for overall skin quality restoration, texture improvement, pore refinement and a healthier, more luminous complexion. It is particularly effective for patients with tired, damaged or ageing skin who want genuine regenerative improvement rather than a temporary glow.
Rejuran I is specifically formulated for the delicate under-eye area — addressing fine lines, crepiness, dark circles and the thinning of periorbital skin that makes the eyes look tired or aged. Its formulation is adapted for this sensitive zone and is one of the most effective under-eye treatments we offer.
Rejuran S targets acne scarring and textural irregularities specifically — with a formulation optimised for dermal remodelling in scarred or damaged skin. For patients with moderate acne scarring, it is frequently combined with microneedling for enhanced channel delivery and results.
Rejuran HB combines polynucleotides with hyaluronic acid — delivering both the regenerative benefits of PN and the immediate hydration of HA in a single treatment. It is ideal for patients who want comprehensive skin improvement alongside visible hydration from the first session.
Results develop progressively over two to four weeks, with optimal improvement seen after a course of two to three sessions spaced three to four weeks apart.
Maintenance every four to six months sustains results long term.
Rejuran does not alter your features. It does not add volume. It makes your skin better — and that difference is visible to everyone who knows what healthy skin looks like.
AESTHETICS AWARDS 2026 WINNER - INJECTABLE PRODUCT OF THE YEAR 2026
Profhilo: Italian Bio-Remodeling Hyaluronic Acid
Profhilo is a revolutionary Italian bio-remodeling treatment using ultra-pure, high-concentration hyaluronic acid to hydrate, lift, and remodel skin from within. Unlike traditional fillers, Profhilo spreads beneath the skin to stimulate collagen and elastin production across the entire face, neck, décolletage, or hands. This slow-release formula delivers deep hydration, improves skin laxity, and restores youthful firmness with natural-looking results. Two sessions, four weeks apart, for transformative rejuvenation.
30 min
From 240 British pounds
PROFHILO — BIO-REMODELLING CARDIFF | PROFHILO & PROFHILO STRUCTURA
Profhilo is not 'technically' a skin booster, but we've popped it here as many people search for it under the skin booster category - and we concede that it kind of is a skin booster! It is not a filler. It is not a hydrator in the conventional sense. Profhilo belongs in its own category — bio-remodelling — and understanding why that distinction matters is the key to understanding what it can actually do for your skin.
Developed by IBSA, one of the world's leading pharmaceutical companies in hyaluronic acid production, Profhilo uses patented NAHYCO® technology to create stabilised hybrid cooperative complexes of high and low molecular weight hyaluronic acid — without any chemical cross-linking agents. This is clinically significant. Cross-linking chemicals, used in most HA products to extend their longevity, carry an inherent inflammatory burden. Profhilo contains none. It is the only stabilised injectable HA product without BDDE on the market, giving it an exceptionally low inflammatory profile and outstanding biocompatibility.
With 64mg of hyaluronic acid per 2ml — one of the highest concentrations of any injectable HA product available — Profhilo does something no standard skin booster can: it spreads. Once injected using the precise Bio Aesthetic Points (BAP) technique — just five injection points per side — the product diffuses through all three layers of the skin, hydrating the epidermis, restructuring the dermis, and remodelling the deeper hypodermis simultaneously. It stimulates four types of collagen and elastin, increases endogenous hyaluronic acid production, and triggers genuine tissue remodelling rather than simply adding moisture.
The clinical result is a visible improvement in skin quality, hydration, elasticity and a subtle but real lifting and tightening effect — without adding volume or changing facial structure. Profhilo makes your skin look better, not different.
We also offer Profhilo Structura — IBSA's more advanced formulation, containing 90mg of HA per 2ml in a denser HCC complex designed specifically for patients with structural volume loss and sagging. Where Profhilo works across the skin layers, Profhilo Structura is injected into the subcutaneous fat compartments to restore adipose tissue, provide a gentle lift and improve facial contour — bridging the gap between skin treatment and structural restoration without the use of traditional dermal filler. A 2024 prospective clinical study confirmed significant improvement in skin elasticity and dermal thickness after two sessions, with high patient satisfaction and minimal adverse events.
Profhilo Structura was named Injectable Product of the Year at the Aesthetics Awards 2026 — the most prestigious industry recognition in UK aesthetic medicine — beating Sculptra, SKINVIVE by Juvéderm, Juvelook and Plinest in the same category. It is the industry's formal acknowledgement of what our patients already know: this is a genuinely exceptional treatment.
At Sebastian Rose we assess each patient individually and advise whether Profhilo, Profhilo Structura or a combination of both is most appropriate for your skin and facial anatomy. Both treatments require two sessions spaced four weeks apart, with results lasting up to six months. Maintenance is recommended every six months.
If your concern is skin quality, laxity, dullness or early structural change — and you want results that are visible to others without looking treated — Profhilo is one of the most consistently rewarding treatments we offer.
Profhilo Structura
Next-generation bio-remodeling with hyaluronic acid, amino acids, and glycerol for advanced lifting and volumizing. Targets deeper skin laxity and volume loss in cheeks, jowls, jawline. Rebuilds skin architecture, restores contours, and improves sagging with powerful rejuvenation.
15 min
From 320 British pounds
PRP Regenerative Facial: Natural Skin Rejuvenation
PRP (Platelet-Rich Plasma) harnesses your body's own healing power to stimulate collagen production, improve skin texture, and reduce fine lines naturally. By concentrating 578+ growth factors from your blood and reinjecting them into the skin, PRP triggers cellular repair and regeneration at the deepest level. Combined with microneedling for enhanced results and long-lasting skin transformation.
30 min
From 280 British pounds
PLATELET RICH PLASMA — CELLENIS PRP CARDIFF
PRP is not a new treatment. It has been used in orthopaedic surgery, wound healing and regenerative medicine for decades. What has changed is the technology used to prepare it — and that difference determines everything about what the treatment can actually achieve.
At Sebastian Rose we use Cellenis — globally recognised as the leading PRP system, originally developed for the medical and surgical market and now the most clinically trusted PRP technology available in aesthetics. Not all PRP is equal. The quality, purity and concentration of the platelet-rich plasma produced depends entirely on the system used to prepare it. Cellenis uses a patented proprietary separation gel and pharmaceutical-grade, internally coated glass tubes that prevent platelets from sticking to the tube walls — a critical technical detail that cheaper systems overlook entirely. The result is a platelet yield of 80 to 95% — meaning the vast majority of platelets in your blood are captured in the final PRP product rather than lost in the separation process.
To put this in context: a standard PRP system might recover 40 to 60% of available platelets. Cellenis consistently delivers 80% or above. Those platelets carry the growth factors — PDGF, TGF-β, VEGF, EGF — that drive collagen synthesis, angiogenesis, tissue repair and skin regeneration. More platelets means more growth factors. More growth factors means better results.
The Cellenis system also removes 99.9% of red blood cells and 95% of granulocytes — the pro-inflammatory white blood cells that, when present in PRP, cause unnecessary swelling, redness and tissue irritation.
What remains is pure, concentrated, non-activated platelet-rich plasma — ready to be injected and to get to work.
PRP from your own blood means zero risk of allergic reaction, zero risk of rejection and no synthetic ingredients of any kind. It is the most natural regenerative treatment available — and when prepared to the standard Cellenis delivers, one of the most effective.
At Sebastian Rose, PRP is used for skin rejuvenation, under-eye treatment, acne scarring, hair restoration and as a powerful add-on to microneedling — where injection immediately after needling drives
RESTYLANE VITAL
Restylane Vital: Hyaluronic Acid Skin Quality Booster
Restylane Vital is a lightweight hyaluronic acid skin booster designed to improve skin quality, hydration, and radiance from within. Using Restylane's advanced NASHA technology, this treatment delivers deep, long-lasting moisture to restore skin smoothness, elasticity, and luminosity. Ideal for treating delicate areas like neck, décolletage, hands, and face where skin appears dull, dehydrated, or crepey. Two to three sessions deliver natural, glowing skin rejuvenation with improved texture and tone.
30 min
249 British pounds
RESTYLANE VITAL — THE ORIGINAL SKIN BOOSTER CARDIFF
Restylane Vital is where the concept of the skin booster began. Developed by Galderma and first CE-certified in Europe in 2004, it invented an entire category of aesthetic treatment — and two decades later, with over nine million treatments performed worldwide, it remains one of the most clinically evidenced injectable skin quality treatments available.
The term "skin booster" is now used loosely across the aesthetics industry to describe dozens of products. Restylane Vital is the original — the product that the term was coined to describe, and the benchmark against which every subsequent skin booster has been measured.
Restylane Vital uses Galderma's patented SB-NASHA technology — stabilised, non-animal, small-particle hyaluronic acid with a specific degree of cross-linking that allows it to integrate into the deep dermis without adding volume or altering structure. Once in place, it attracts and retains water at a cellular level, restoring the skin's hydrobalance — the internal hydration equilibrium that diminishes with age, sun exposure and environmental stress. At the same time, it stimulates fibroblast activity and promotes the production of collagen, elastin and the skin's own endogenous hyaluronic acid — delivering improvement that builds progressively across a course of treatment.
Clinically, Restylane Vital has been shown to improve skin surface roughness, elasticity, brightness, moisture content and fine line appearance — with effects demonstrated to last up to fifteen months in clinical studies. That longevity significantly exceeds most comparable skin quality treatments and is one of the key reasons it has retained its position as a gold standard after twenty years in clinical practice.
We offer both Restylane Vital and Restylane Vital Light at Sebastian Rose. Vital is formulated for more mature or sun-damaged skin, injected into the deep dermis where hydration and collagen support are most needed. Vital Light is a finer formulation for younger skin, preventative treatment, or more delicate areas — delivering the same fundamental skin quality benefits at a lighter concentration suited to patients in their thirties or those with thinner, more sensitive skin.
Both are suitable for face, neck, décolletage and hands. A course of three sessions spaced four weeks apart is recommended, followed by maintenance every six months. Treatment includes lidocaine for patient comfort.
Restylane Vital does not add volume. It does not change your features. It makes your skin healthier, more hydrated and more radiant — and it has been doing exactly that, consistently, for over twenty years.
Sculptra: Collagen-Stimulating Biostimulator for Lasting Volume
Sculptra is a biostimulatory injectable using poly-L-lactic acid (PLLA) to gradually restore facial volume, smooth wrinkles, and improve skin quality by triggering your body's own collagen production. Unlike traditional fillers that simply add volume, Sculptra rebuilds your skin's underlying structure for natural-looking results that develop subtly over months and last up to two years. Ideal for sunken cheeks, hollow temples, deep folds, and overall facial aging. Progressive rejuvenation from within for long-lasting transformation.
30 min
From 250 British pounds
SCULPTRA — POLY-L-LACTIC ACID BIOSTIMULATOR CARDIFF
Sculptra is not a filler. It does not add volume in the way dermal fillers do and it does not hydrate the skin in the way a skin booster does. Sculptra is a collagen biostimulator — and what it stimulates is your body's own structural foundation.
The active ingredient in Sculptra is poly-L-lactic acid (PLLA) — a synthetic, biodegradable polymer that has been used safely in medicine for decades, most notably in dissolvable sutures. When injected into the deep dermis and subcutaneous tissue, the PLLA microparticles trigger a controlled inflammatory response that activates fibroblasts — the cells responsible for producing collagen. Over the following weeks and months, your body lays down new collagen fibres in the treated areas, gradually restoring the structural scaffolding that is lost through ageing.
The PLLA itself is fully biodegradable and is completely reabsorbed by the body — what remains is your own collagen.
This mechanism produces results that are fundamentally different from anything a filler or skin booster can achieve. Rather than an immediate change, Sculptra delivers gradual, progressive improvement that builds over three to six months — and because the result is your own collagen rather than an injected product, it looks and feels entirely natural. Results are typically maintained for two years or more, making Sculptra one of the longest-lasting non-surgical treatments available.
Clinically, Sculptra is indicated for volume loss in the mid and lower face, temple hollowing, jawline softening, skin laxity, and the treatment of deep folds and structural ageing changes. It is particularly well suited to patients who want to address the cause of facial ageing — the loss of collagen and structural support — rather than temporarily masking the symptoms with filler. It is also increasingly used for skin quality and texture improvement, neck and décolletage rejuvenation, and body treatments including the buttocks and knees (note: we do not offer Sculptra buttocks or knees)
Sculptra is a Galderma product — the same company behind Azzalure, Alluzience and Restylane Vital, whose products we know, trust and use daily. It is MHRA-licensed, has an outstanding long-term safety profile, and has been used in aesthetic medicine for over twenty years.
Treatment typically involves two to three sessions spaced six to eight weeks apart, with results developing progressively and peaking at three to six months.
We will assess suitability, discuss realistic outcomes and determine the correct treatment plan for your anatomy and goals.
Sculptra is not suitable for every patient — honest clinical assessment always comes first.
SKINVIVE
Skinvive: FDA-Approved Hyaluronic Acid Microdroplet Treatment
Skinvive is an innovative hyaluronic acid injectable designed to improve skin smoothness, hydration, and overall quality using microdroplet technique. Unlike traditional dermal fillers that add volume, Skinvive enhances skin texture from within, creating a natural glow and dewiness. This single-session treatment delivers lasting hydration and radiance for 6-9 months, making it ideal for those seeking subtle skin quality improvement without altering facial contours. Perfect for achieving healthy, glowing, well-hydrated skin.
30 min
250 British pounds
SKINVIVE BY JUVÉDERM — MICRODROPLET SKIN BOOSTER CARDIFF
Skinvive by Juvéderm sits in its own category. It is not a filler — it adds no volume and does not alter facial structure. It is not a traditional skin booster in the Profhilo or Restylane Vital sense. Skinvive is a microdroplet injectable — a completely distinct approach to skin quality improvement that uses the precision of Juvéderm's manufacturing and the hydrating power of hyaluronic acid to do something no topical product can: hydrate the skin from within, at a structural level, and sustain that hydration for months.
Developed by Allergan Aesthetics — one of the world's most clinically rigorous aesthetics companies and the maker of Botox — Skinvive uses a proprietary cross-linked hyaluronic acid formulation delivered as thousands of uniform microdroplets across the skin's surface layer. Rather than depositing product in a single location, the microdroplet technique bathes the treated area in a fine, even distribution of hyaluronic acid — attracting water, binding it within the dermis, and creating a sustained internal moisture reservoir that improves skin smoothness, texture and radiance as it integrates over the following weeks.
The mechanism that makes Skinvive particularly effective is its impact on aquaporins — the proteins responsible for transporting water into skin cells. By increasing aquaporin activity, Skinvive enhances the skin's fundamental ability to hydrate itself, producing an improvement that goes beyond any external moisturiser or topical serum. The clinical result is skin that looks genuinely healthier — more luminous, smoother in texture, softer to touch, and possessed of that lit-from-within glow that patients consistently describe and that photographs simply cannot replicate.
In clinical studies, patients reported high satisfaction with skin glow, hydration and radiance at six months — with some reporting sustained improvement beyond nine months. It is one of the longest-lasting skin quality injectables available in terms of results-to-downtime ratio, and requires no structural assessment or complex planning. It is a treatment for people who want their skin to look better without looking treated.
Skinvive is particularly well suited to patients in their late twenties through to their fifties who are experiencing dullness, mild texture irregularities, or dehydration — and who want a subtle, consistent improvement rather than visible correction. It works exceptionally well alongside other treatments including botulinum toxin, dermal fillers and polynucleotides, and is an excellent maintenance treatment between more intensive courses.
Treatment takes approximately thirty minutes. Results are visible within days and continue to develop over two to four weeks. A single treatment provides results lasting six to nine months — many patients choose to repeat twice yearly. Minimal downtime. Contains lidocaine for comfort.
SEVENTY HYAL
Seventy Hyal 2000: High-Molecular-Weight Skin Booster
Seventy Hyal 2000 is an advanced hyaluronic acid skin booster featuring ultra-high molecular weight HA for deep, long-lasting hydration and skin quality improvement. This treatment delivers intense moisture, improves elasticity, smooths fine lines, and enhances overall skin radiance from within. The high-molecular-weight formula provides superior hydration retention and longer-lasting results compared to standard skin boosters. Ideal for dehydrated, dull, or aging skin seeking comprehensive rejuvenation. Two to three sessions for glowing, plumped, revitalized skin.
15 min
From 199 British pounds
SEVENTY HYAL 2000 — HIGH MOLECULAR WEIGHT SKIN BOOSTER CARDIFF
Most skin boosters do one thing well. Seventy Hyal 2000 does three simultaneously — and the science behind why that's possible comes down to molecular weight.
Seventy Hyal 2000 is a CE-marked injectable hyaluronic acid skin booster with a molecular weight of over 2000 kDa — one of the highest molecular weight HA formulations available in the injectable skin booster market. Molecular weight is not a marketing term. It is a fundamental chemical property that determines how a hyaluronic acid molecule behaves once it is inside your skin. Higher molecular weight molecules integrate at mid-dermal depth, hold significantly more water per molecule, resist enzymatic breakdown more effectively, interact with fibroblast cells more robustly, and persist in the tissue for longer than lower molecular weight alternatives. The result of this high molecular weight is a skin booster that doesn't simply hydrate and disappear — it integrates into the dermal architecture, sustains moisture, progressively stimulates collagen and elastin production, and delivers a subtle but visible volumising effect as the highly hydrophilic HA draws and binds water within the dermis.
The three outcomes Seventy Hyal 2000 delivers simultaneously — and that most skin boosters address individually — are hydration, glow and gentle contour. The intense surge of hydration is immediate, with visible results often apparent within days of treatment. The collagen and elastin stimulation builds progressively over the following weeks, improving skin quality, texture and firmness over time. And the gentle volumising effect — a soft, natural restoration of fullness — is particularly noticeable in the lower face, where the subtle lifting effect of this dense, viscous formulation is most clinically apparent.
With 90mg of hyaluronic acid per 6ml — a high concentration relative to comparable products — Seventy Hyal 2000 is also one of the more substantive skin booster formulations in terms of raw HA content. It is exclusively distributed in the UK through Fox Pharma, one of the most trusted pharmaceutical distributors in UK aesthetics, and has been reviewed and featured in the Journal of Aesthetic Nursing, where early clinical results were described as impressive.
Seventy Hyal 2000 is suitable for all skin types and tones, requires no numbing cream for most patients, and can be used on the face, neck, décolletage and hands. It is particularly well suited to patients who want comprehensive skin quality improvement — hydration, glow and gentle structural support — rather than a single focused outcome.
A course of two to three sessions spaced four weeks apart is recommended, with maintenance every six to twelve months. Results are visible almost immediately, with full effect at two weeks.
Sunekos Bio-Revitalization
Hyaluronic acid with patented amino acid complex stimulating both collagen and elastin production. Restores the Extra Cellular Matrix, improving hydration, elasticity, and firmness from within. Ideal for under-eyes, hands, neck, décolletage. Natural regeneration and lasting quality improvement.
20 min
499 British pounds
PLATELET RICH PLASMA (PRP) harnesses the power of your own blood - specifically platelets, to rejuvenate the under eye area. Suitable for all skin types and all under eye conditions.
COST: £99 per session.
SUNEKOS — AMINO ACID & HYALURONIC ACID BIO-REGENERATION CARDIFF
Sunekos is the treatment that addresses something most skin boosters simply cannot — elastin.
Collagen gets the majority of attention in aesthetic medicine and rightly so. But elastin is the protein responsible for your skin's ability to spring back into shape — its resilience, its bounce, its resistance to gravity. After the age of approximately 40, elastin production drops dramatically and unlike collagen, it is extremely difficult to stimulate through conventional injectable treatments. Sunekos is specifically designed to address this gap.
Developed in Italy by Professional Dietetics and manufactured as a CE-marked Class III medical device, Sunekos uses a patented formula called HY6AA — a precise combination of low molecular weight hyaluronic acid and six specific amino acids: glycine, L-proline, L-leucine, L-lysine, L-valine and L-alanine. These amino acids are not chosen randomly. They are the exact molecular building blocks that fibroblast cells in the dermis require to synthesise both collagen and elastin. When injected into the dermis, Sunekos delivers these building blocks directly to the fibroblasts — triggering a natural, physiological regeneration of the extracellular matrix, the structural scaffolding that gives healthy skin its firmness, elasticity and resilience.
What makes Sunekos clinically unique is twofold.
First, it is one of the only injectable treatments with a demonstrated effect on elastin production — a distinction that is particularly significant for patients with crepey, lax or thin skin where elastin loss is the primary concern.
Second, a clinical study published in the Journal of Clinical Trials found that the HY6AA formula actively inhibits hyaluronidase — the enzyme responsible for breaking down hyaluronic acid in the skin — meaning Sunekos not only delivers hydration but actively protects the skin's own existing hyaluronic acid reserves.
Clinical results have shown forehead wrinkle reduction of up to 71%, a 49% reduction in the appearance of sun damage, and a 50% improvement in skin firmness. Improvements were statistically significant at ten days post-treatment and continued improving for six months after the final session.
Sunekos does not add volume. It does not alter facial structure. It regenerates the quality and health of your skin from within — and it does so in areas where other treatments have limited effect. It is particularly outstanding for thin, crepey or delicate skin, the under-eye area, the neck, décolletage, inner arms, knees and hands — areas where the skin is too fragile for conventional fillers and where collagen and elastin loss is most visibly apparent.
At Sebastian Rose we offer Sunekos 200 (Performa) for fine lines, mild laxity and delicate treatment areas, and Sunekos 1200 for more significant skin laxity, deeper concerns and patients requiring greater structural regeneration. Your practitioner will recommend the appropriate formulation at consultation.
A course of three to four sessions spaced one to two weeks apart is typically recommended, with maintenance every six months. Treatment takes approximately thirty minutes with minimal downtime.
Teosyal Redensity I: Swiss Skin Quality Enhancer
Teosyal Redensity I is a premium skin quality treatment combining hyaluronic acid with essential nutrients, amino acids, antioxidants, minerals, and vitamins to restore radiance, hydration, and vitality. This unique bio-revitalizing formula improves skin texture, reduces fine lines, and enhances overall luminosity while protecting against oxidative stress and environmental damage. Ideal for tired, dull, dehydrated skin seeking comprehensive rejuvenation. Results develop progressively with a treatment course of two to three sessions for glowing, revitalized, healthy skin.
30 min
From 199 British pounds
TEOSYAL REDENSITY I — NUTRIENT-RICH SKIN BOOSTER CARDIFF
Most skin boosters deliver one active ingredient — hyaluronic acid. Teosyal Redensity I delivers fourteen.
Developed by Teoxane Laboratories in Geneva, Switzerland — one of the most respected names in injectable product development globally — Teosyal Redensity I is a CE-marked, non-cross-linked hyaluronic acid skin booster formulated with a patented Redensity Complex: a precisely calibrated cocktail of fourteen bioactive nutrients that are naturally present in healthy skin and progressively depleted by ageing, sun exposure and environmental stress.
The formula contains high molecular weight hyaluronic acid at 15mg/ml for deep dermal hydration and elasticity restoration. It combines this with eight specific amino acids — arginine, glycine, lysine, threonine, proline, isoleucine, leucine and valine — which are the direct building blocks of collagen and elastin, delivered exactly where fibroblasts need them to initiate new collagen synthesis and cell regeneration. Three powerful antioxidants — glutathione, N-acetyl-L-cysteine and alpha-lipoic acid — protect the skin from free radical damage and oxidative stress, one of the primary drivers of premature skin ageing. Vitamin B6 supports cell metabolism and renewal. And two minerals — zinc and copper — contribute to overall skin health, wound repair and enzymatic function.
The clinical significance of this combination is substantial. Where a standard hyaluronic acid skin booster hydrates and temporarily plumps, Teosyal Redensity I actively nourishes the skin's biological machinery — providing the raw materials for genuine regeneration rather than surface-level improvement. A 2025 prospective clinical study published in the Journal of Cosmetic Dermatology confirmed meaningful improvements in skin hydration, elasticity and density following a course of Redensity I treatment. A separate retrospective study using high-frequency ultrasound imaging demonstrated measurable increases in dermal density following a single cannula-delivered treatment in the midface region.
Teosyal Redensity I is delivered via microinjection into the superficial dermis and contains lidocaine for patient comfort. It is suitable for the face, neck, décolletage and hands — including delicate and sensitive areas where many other skin boosters are not recommended. It is CE-marked, manufactured in Switzerland to pharmaceutical standards, and sourced exclusively from verified UK distributors at Sebastian Rose.
It does not add volume. It does not change your features. It feeds your skin everything it needs to repair, regenerate and glow from within — and it does so with fourteen clinically selected ingredients working simultaneously rather than one.
A course of three sessions spaced three weeks apart is recommended, with maintenance every six to nine months. Results last up to nine to twelve months with optimal treatment.
WOW FUSION
WOW Fusion
Microneedling with bespoke serum cocktails—hyaluronic acid, vitamins, peptides, brightening, anti-aging. 20 gold-plated needles deliver customized blends deep into skin. Targets multiple concerns. Instant glow, progressive improvement.
15 min
From 150 British pounds
WOW FUSION — BESPOKE MICRONEEDLING MESOTHERAPY CARDIFF
Most treatments give every patient the same thing. WOW Fusion gives every patient something different — and that is the entire point.
WOW Fusion is a medical device and treatment protocol that fuses three distinct approaches in a single procedure: microneedling, mesotherapy and bespoke skin nutrition. The device contains 20 ultra-fine, 24-karat gold-plated titanium needles — each just 0.13mm in diameter — attached to a glass vial containing your personalised treatment cocktail, blended on the day by your practitioner specifically for your skin, your concerns and your goals on that particular visit. No two WOW Fusion treatments are identical.
Here is what makes the device clinically intelligent: as the needles create precision micro-channels in the skin at the epidermal-dermal junction, your bespoke cocktail flows simultaneously through those channels and is delivered directly into the dermis. This is fundamentally different from applying actives topically after needling — the delivery is concurrent, precise, and reaches a depth that no topical product can penetrate. The result is a treatment that stimulates collagen and elastin through the mechanical action of microneedling, while simultaneously infusing the skin with exactly the active ingredients it needs at exactly the right depth.
The cocktail is built around your skin's specific needs at consultation. Hyaluronic acid for deep hydration and plumping. Vitamin C and antioxidants for brightening and pigmentation. B-complex vitamins and amino acids for cell renewal and collagen support. Peptides for matrix regeneration and firmness. And where appropriate — micro-tox: a small, precisely dosed addition of diluted botulinum toxin to reduce oil production, minimise pore size, control sebum and refine skin texture without affecting facial movement. This is the treatment's unique advantage — the combination of regenerative mesotherapy with the pore-refining, oil-controlling properties of micro-tox, all delivered in a single appointment.
The glow that follows a WOW Fusion treatment is immediate and distinctive. Skin looks visibly brighter, more hydrated and more refined within hours — and continues to improve in the days and weeks that follow as the collagen response builds. Results from a single treatment last four to six weeks. A course of three to four sessions, spaced four to six weeks apart, delivers cumulative improvement in skin quality, texture, tone and radiance that builds progressively with each session.
WOW Fusion is suitable for all skin types and tones.
Downtime is minimal — mild redness for a few hours at most.
It works brilliantly as a standalone treatment and as a complement to other skin treatments including Profhilo, polynucleotides, chemical peels and laser. It is one of our most versatile and most popular skin treatments at Sebastian Rose — and it is genuinely impossible to replicate the personalised nature of what is formulated and delivered in each session.
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